Research Keyword: Scale-up production

The differences between broad bean koji fermented in laboratory and factory conditions by an efficient Aspergillus oryzae

This study compared how two types of A. oryzae fungi ferment broad beans to make koji, a starter ingredient for Chinese broad bean paste. Researchers tested the same fungi in small laboratory batches and large factory batches to see if what works in the lab also works in industry. They found that the factory’s larger scale and different environment actually had a bigger impact on the final product than which specific fungus strain was used, though the PN strain was still efficient overall.

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Enhanced extracellular production of laccase in Coprinopsis cinerea by silencing chitinase gene

Scientists enhanced the production of laccase, a useful enzyme with industrial applications, in a type of mushroom by silencing specific genes involved in cell wall construction. The modified mushroom strain could withstand stronger mixing forces during fermentation, leading to significantly higher enzyme yields. This genetic engineering approach could help make laccase production more efficient and cost-effective for industrial uses like detoxification and food processing.

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