Research Keyword: Safety evaluation

Bioactivity and toxicity of polysaccharides derived from the phytopathogenic mushroom Ganoderma orbiforme cultured in a bioreactor

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Scientists studied a mushroom called Ganoderma orbiforme that normally harms oil palm trees to see if it could be useful as medicine. They grew the mushroom in a special bioreactor and extracted beneficial substances called polysaccharides. These substances showed promise as natural antibiotics and antioxidants while being safe for use based on safety testing with fish embryos.

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Updated safety evaluation of the food enzyme AMP deaminase from the non‐genetically modified Streptomyces murinus strain AE‐DNTS

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Scientists evaluated the safety of AMP deaminase, an enzyme used in food processing for yeast and mushroom extract production. The enzyme is produced from a naturally occurring bacterium and is intended to help break down adenosine monophosphate during food manufacturing. Through extensive testing including genetic mutation tests and animal studies, researchers found no safety concerns when used at recommended levels in food processing. The amount of enzyme that consumers might ingest through food is far below levels that could cause any adverse effects.

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Updated safety evaluation of the food enzyme AMP deaminase from the non‐genetically modified Streptomyces murinus strain AE‐DNTS

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This study evaluated the safety of an enzyme called AMP deaminase that is used in food processing, particularly for making yeast products and mushroom extracts. Researchers tested the enzyme for genetic damage and toxicity using laboratory studies. The results showed the enzyme is safe for use in food manufacturing at the recommended levels, with a very large safety margin between the amounts used in food and amounts that might cause harm.

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