Farmers in semi-arid regions like Morocco often irrigate crops with water containing toxic cyanobacterial compounds called microcystins, which accumulate in food crops and harm human health. This study showed that inoculating faba bean plants with beneficial soil bacteria, particularly Achromobacter marplatensis, reduced microcystin accumulation in plants by 36% and promoted healthier plant growth despite contaminated water. The approach offers an affordable, sustainable solution to protect food crops in areas with microcystin-contaminated irrigation water.