Research Keyword: rhino-orbital-cerebral mucormycosis

Clinical Challenges and Predictive Risk Factors for Outcomes in COVID-19–Associated Mucormycosis

During the COVID-19 pandemic, a dangerous fungal infection called mucormycosis has become a serious complication, especially for patients with uncontrolled diabetes or those taking certain medications. Researchers studied 180 patients with this condition and found that the infection can spread from the sinuses to the eyes and brain, leading to severe outcomes. The most important factors in surviving this infection are early detection, keeping blood sugar controlled, careful use of steroids, and aggressive treatment with antifungal medications and sometimes surgery.

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Rhino-orbital-cerebral mucormycosis in diabetic ketoacidosis: A classic clinical presentation still unknown in Senegal

A young woman in Senegal with uncontrolled diabetes developed a serious fungal infection affecting her eye and brain caused by Rhizopus oryzae. Despite showing classic warning signs like swelling and tissue death, the infection was not diagnosed quickly enough, and the necessary antifungal medication (amphotericin B) was not available, resulting in her death within three days. This case highlights how invasive fungal infections are underrecognized and undertreated in Africa due to limited laboratory capacity and drug availability.

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