Research Keyword: RFLP-PCR

Detection of Opportunistic Fungi from the Bronchoalveolar Lavage Specimens of Patients with Pulmonary Diseases

Researchers examined lung fluid samples from patients with lung diseases to identify fungal infections. They found various types of fungi including Aspergillus, Penicillium, and Pneumocystis using microscopy and laboratory tests. Large numbers of fungi were present in many samples, which could interfere with medicine absorption and treatment. The study shows that quick and accurate identification of these fungi is important for treating lung infections properly.

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Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

A 13-year-old boy developed a serious fungal infection on his replacement heart valve after recent surgery. The fungal infection was caused by a type of yeast called Candida glabrata that was resistant to the initial antifungal medication. After testing revealed resistance and biofilm formation, doctors switched to caspofungin, a stronger antifungal drug, and the patient recovered successfully.

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Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

A 13-year-old boy developed a serious fungal infection of his heart valve after surgery. The infection was caused by a resistant yeast that didn’t respond to initial antifungal treatment. Doctors used molecular testing to identify the exact fungal species and tested how it responded to different medications. After switching to a different antifungal drug called caspofungin, the patient recovered completely and remained healthy.

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Caspofungin therapy in prosthetic valve endocarditis and candidemia due to itraconazole-resistant Candida glabrata (Nakaseomyces glabratus): A case report

A 13-year-old boy developed a serious fungal infection of his heart valve after receiving an artificial valve replacement. The initial antibiotic (itraconazole) did not work because the fungus became resistant, likely by forming a protective biofilm. After identifying the resistant fungus through specialized testing, doctors switched to a different medication called caspofungin. The patient fully recovered with this new treatment and remained healthy during follow-up, showing that combination of precise identification and targeted treatment can overcome antibiotic resistance.

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