Research Keyword: resistance

Evaluation of the Cytotoxicity and Antifungal Efficacy of Crocus sativus (saffron) Petals on Clinical Isolates of Candida albicans

Researchers tested saffron petals as a natural antifungal treatment against Candida albicans, a common fungal infection. While the saffron extract was less potent than the standard drug fluconazole, it showed promise as a safer alternative with minimal toxicity to human cells. The findings suggest saffron petals could be a cost-effective herbal option for treating fungal infections, especially as resistance to conventional antifungals increases.

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Tracing the Origin and Evolution of the Fungal Mycophenolic Acid Biosynthesis Pathway

Mycophenolic acid is an important drug that helps transplant patients by preventing their immune systems from rejecting new organs. Scientists studied the genes that fungi use to make this drug and found it in several fungal species. They discovered that this ability to produce the drug evolved a long time ago in fungi but was lost in most species over time, remaining only in a few special fungi.

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