Research Keyword: recombinant DNA technology

Harnessing the yeast Saccharomyces cerevisiae for the production of fungal secondary metabolites

Scientists have learned to use common baker’s yeast (S. cerevisiae) as a biological factory to produce valuable medicines and compounds that naturally come from fungi and mushrooms. By transferring the genetic instructions for making these compounds into yeast cells and improving them with genetic engineering, researchers can now produce therapeutically important substances like cancer-fighting drugs and antibiotics in large quantities. This approach is more practical and cost-effective than trying to extract these rare compounds directly from their native fungal sources or using other production methods.

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Diverse origins of fibrinolytic enzymes: A comprehensive review

Blood clots can cause heart attacks and strokes, which are major causes of death worldwide. Currently used clot-dissolving drugs have significant drawbacks including short effectiveness periods and side effects. This review examines how fibrinolytic enzymes—naturally occurring proteins that dissolve blood clots—can be obtained from various sources, especially fermented foods like Japanese natto. These enzymes show promise as safer, cheaper alternatives that could be produced in large quantities for treating cardiovascular diseases.

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