Research Keyword: Reactive oxygen species

Modulation of Abortiporus biennis Response to Oxidative Stress by Light as a New Eco-Friendly Approach with a Biotechnological Perspective

Researchers studied how different colored lights and a chemical called menadione affect a white rot fungus called Abortiporus biennis. They found that combining red light with menadione significantly increased the fungus’s metabolic activity and production of useful compounds like laccase, an enzyme with industrial and medical applications. The study shows that using simple, eco-friendly stressors like colored light could help boost the fungus’s beneficial properties for practical use.

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Cestrum tomentosum L.f. Extracts against Colletotrichum scovillei by Altering Cell Membrane Permeability and Inducing ROS Accumulation

Researchers found that extracts from the Cestrum tomentosum plant effectively kill a fungus that causes anthracnose disease in chili peppers. The plant extract works by damaging the fungal cell membranes and causing harmful reactive oxygen species to accumulate inside fungal cells. This natural remedy showed strong protective and therapeutic effects when applied to chili pepper fruits, offering a safer alternative to synthetic chemical fungicides.

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Graphene nanomaterials: A new frontier in preventing respiratory fungal infections

Fungal lung infections are a serious problem, especially for people with weak immune systems. Researchers are exploring graphene nanomaterials as a new treatment approach that can deliver antifungal drugs directly to infected areas in the lungs. These tiny particles work by creating toxic stress inside fungal cells and breaking down their protective biofilms, while using smaller drug doses and causing fewer side effects than traditional treatments.

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Effects and molecular mechanism of endophytic elicitors on the accumulation of secondary metabolites in medicinal plants

This review explains how beneficial fungi living inside medicinal plants can boost the production of healing compounds. These endophytic fungi act as natural triggers that activate the plant’s own defense systems, causing it to produce more of the valuable medicinal substances used in traditional and modern medicine. By understanding how this process works, scientists can develop better methods to grow medicinal plants and produce natural drugs more sustainably without depleting wild plant populations.

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High temperature enhances the ability of Trichoderma asperellum to infect Pleurotus ostreatus mycelia

Researchers discovered that summer heat makes oyster mushroom crops more vulnerable to green mold disease caused by a fungus called Trichoderma asperellum. When exposed to high temperatures (36°C), the pathogenic fungus becomes more aggressive by producing more spores, germinating faster, and generating molecules like hydrogen peroxide that damage the mushroom mycelia. Meanwhile, the oyster mushroom itself becomes more susceptible to infection at these higher temperatures, explaining why green mold outbreaks are so common during hot summer months in mushroom farms.

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In vitro activity of seven antifungal agents against Fusarium oxysporum and expression of related regulatory genes

Researchers tested seven different antifungal medications to find the best treatment for a fungal disease that damages corn crops. Epoxiconazole worked best as a single treatment, but combining pyraclostrobin and difenoconazole together was even more effective. These medications work by interfering with the fungus’s ability to survive and infect corn, making them promising options for protecting corn crops.

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Cinchona-based liquid formulation exhibits antifungal activity through Tryptophan starvation and disruption of mitochondrial respiration in Rhizoctonia Solani

Scientists discovered that a liquid extract from Cinchona bark, which contains quinine, can effectively kill a fungus that damages rice crops. The treatment works by blocking the fungus’s ability to absorb tryptophan (an important amino acid) and damaging its energy-producing mitochondria. When tryptophan was added back to the treatment, the fungus recovered, confirming this is the main way the extract works. This natural, plant-based approach could provide an eco-friendly alternative to chemical fungicides while reducing the risk of the fungus developing resistance.

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Fungal-fungal cocultivation alters secondary metabolites of marine fungi mediated by reactive oxygen species (ROS)

Researchers discovered that when two types of ocean fungi grow together, one of them produces a protective chemical called alternariol that can kill bacteria and cancer cells. This happens because the fungi recognize each other as competitors and trigger special stress signals that activate defensive chemical production. Interestingly, fungi from the ocean respond differently than those from land, suggesting they have evolved unique survival strategies for harsh marine environments.

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Modulation of Abortiporus biennis Response to Oxidative Stress by Light as a New Eco-Friendly Approach with a Biotechnological Perspective

Researchers studied how a type of fungus called Abortiporus biennis responds to stress created by a chemical compound (menadione) and different colors of light. They found that combining white light with menadione dramatically increased the production of laccase, an important enzyme used in industrial applications. This discovery offers an inexpensive, non-toxic way to boost enzyme production without using expensive chemical additives, potentially improving medical and industrial uses of this fungus.

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Antioxidant Potential-Rich Betel Leaves (Piper betle L.) Exert Depigmenting Action by Triggering Autophagy and Downregulating MITF/Tyrosinase In Vitro and In Vivo

This research shows that betel leaves, a traditional herb used in Asian cultures, can lighten skin pigmentation through multiple mechanisms. The extract works by reducing tyrosinase enzyme activity, activating cellular cleanup processes called autophagy, and boosting the body’s natural antioxidant defenses. In both laboratory cells and living mice exposed to UV radiation, betel leaves extract effectively reduced unwanted skin darkening, suggesting it could be developed into safe natural skin-whitening products.

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