Research Keyword: Reactive oxygen species

Effect of Nutraceutical Supplementation and Mediterranean Hypocaloric Diet on Calculated Steatosis Indices and Inflammation: Clinical and In Vitro Evidences

This research shows that taking a specialized supplement containing natural plant compounds along with eating a Mediterranean diet can significantly help people with fatty liver disease. The supplement works by reducing harmful stress molecules in liver cells and calming down inflammation. After three months of treatment, patients showed improved liver health markers, better cholesterol levels, and improved blood sugar control. The study demonstrates that combining diet and targeted supplements is more effective than diet changes alone.

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Therapeutic and Nutraceutical Potential of Sargassum Species: A Narrative Review

Sargassum is a type of ocean seaweed that has been used in traditional medicine for centuries and contains compounds that may help fight inflammation, oxidative stress, viruses, and bacteria. Scientists have discovered that different Sargassum species produce nearly 200 different bioactive compounds with potential health benefits ranging from reducing arthritis symptoms to supporting immune function. While Sargassum can accumulate harmful heavy metals like arsenic from seawater, researchers have developed effective cleaning methods to remove these contaminants while preserving the beneficial compounds. This makes Sargassum a promising sustainable source of natural medicines and health supplements.

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Effects and safety of Psilocybe cubensis and Panaeolus cyanescens magic mushroom extracts on endothelin-1-induced hypertrophy and cell injury in cardiomyocytes

Researchers tested whether magic mushrooms containing psilocybin could be safely used by people with heart failure, especially those dealing with depression. Using laboratory rat heart cells, they found that extracts from Psilocybe cubensis and Panaeolus cyanescens mushrooms actually protected heart cells from damage and reduced harmful inflammation. The mushroom extracts worked similarly to standard heart medications at the tested concentrations, suggesting they may be safe for use under controlled medical supervision.

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Exogenous MnSO4 Improves Productivity of Degenerated Volvariella volvacea by Regulating Antioxidant Activity

This study shows that adding manganese sulfate to degenerated mushroom strains can restore their ability to grow and produce fruit bodies. The treatment works by improving the mushrooms’ natural defense systems against damaging free radicals and enhancing enzymes that break down the growing medium. Results showed significantly improved growth rates, shorter production times, and even allowed severely damaged strains to produce mushrooms again.

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Antioxidative Activities of Micronized Solid-State Cultivated Hericium erinaceus Rich in Erinacine A against MPTP-Induced Damages

Researchers tested a processed form of Lion’s mane mushroom (Hericium erinaceus) to see if it could protect against Parkinson’s disease-like damage in mice. The mushroom mycelium was specially processed to break down cell walls and increase its effectiveness. When given to mice exposed to a Parkinson’s-causing toxin, the mushroom treatment restored dopamine levels and reduced harmful oxidative stress in the brain and liver in a dose-dependent manner.

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Traditional Chinese Medicine for Hashimoto’s Thyroiditis: Focus on Selenium and Antioxidant Phytochemicals

Hashimoto’s thyroiditis is a common autoimmune thyroid disease that often leads to symptoms like fatigue and reduced quality of life. While standard treatment uses thyroid hormone replacement, it doesn’t address the underlying inflammation and oxidative stress. This review explores how traditional Chinese medicine approaches, often combined with selenium, may help reduce thyroid antibodies and improve symptoms through their antioxidant and anti-inflammatory properties.

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Green-Synthesized Nanomaterials from Edible and Medicinal Mushrooms: A Sustainable Strategy Against Antimicrobial Resistance

Scientists are developing a new weapon against antibiotic-resistant bacteria using mushrooms. These special nanoparticles derived from edible and medicinal mushrooms can kill harmful bacteria in multiple ways without the toxic chemicals used in traditional manufacturing. The nanoparticles work by disrupting bacterial membranes, creating harmful molecules called free radicals, and even boosting your body’s natural immune response. This environmentally friendly approach could become an important tool in fighting dangerous infections that don’t respond to current antibiotics.

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Therapeutic and Preventive Potential of Plant-Derived Antioxidant Nutraceuticals

This comprehensive review explores how compounds found in plants can protect our bodies from harmful damage caused by oxidative stress, which is linked to aging and various diseases. Plant-based foods rich in antioxidants like berries, leafy greens, and olive oil contain special molecules that can help prevent cancer, heart disease, diabetes, and other chronic conditions. The review highlights that these natural compounds work through multiple beneficial mechanisms beyond just antioxidant activity, making plant-based diets an effective strategy for maintaining health and preventing disease.

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Exogenous L-Arginine Enhances Pathogenicity of Alternaria alternata on Kiwifruit by Regulating Metabolisms of Nitric Oxide, Polyamines, Reactive Oxygen Species (ROS), and Cell Wall Modification

Researchers discovered that a specific nutrient called L-arginine paradoxically makes a fungus that causes black spot on kiwifruit more dangerous at low concentrations. The fungus uses this amino acid to trigger multiple survival mechanisms including producing protective molecules and enzymes that break down plant cell walls. However, at higher concentrations, L-arginine actually inhibits the fungus, suggesting it could be used as part of a disease control strategy.

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Study on the inhibitory mechanism of fig leaf extract against postharvest Fusarium in melon

Researchers discovered that fig leaves contain natural compounds that can prevent fruit rot caused by Fusarium fungus in melons. When applied to infected melons, the fig leaf extract kills the fungus by damaging its cell membranes and overwhelming it with harmful molecules called reactive oxygen species. This natural treatment could replace chemical fungicides that harm the environment and leave residues on food, offering a safer way to preserve melons during transport and storage.

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