Research Keyword: rapid diagnosis

Development of reverse transcription loop-mediated isothermal amplification-based assay for rapid and specific detection of human fungal pathogen, Candida auris

Researchers developed a new rapid test called RT-LAMP to detect Candida auris, a dangerous multidrug-resistant fungus that causes hospital infections. The test works by changing color from pink to yellow when the fungus is present, making it easy to read without special equipment. It is more sensitive and specific than current methods, can be done quickly at a single temperature, and costs much less than existing tests, making it ideal for hospitals and clinics with limited resources.

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Advances in Fungal Infection Research: From Novel Diagnostics to Innovative Therapeutics

Fungal infections are becoming increasingly serious, especially for people with weakened immune systems, and some fungi are developing resistance to current medications. Researchers are developing faster diagnostic tests using molecular techniques and exploring new treatment approaches including repurposing existing drugs and developing vaccines. Monitoring and prevention programs in hospitals are essential to control the spread of these infections and improve patient outcomes.

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An Automated and Highly Sensitive Chemiluminescence Immunoassay for Diagnosing Mushroom Poisoning

Poisoning from deadly mushrooms like Amanita phalloides kills about 90% of poisoning victims. Current methods to diagnose these poisonings take too long for doctors to help patients quickly. This study describes a new automated test that can detect the toxic compounds (phallotoxins) in patient blood and urine in just 45 minutes with very high accuracy, potentially saving lives by enabling faster medical treatment.

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Diagnostic Approaches to Invasive Candidiasis: Challenges and New Perspectives

Invasive candidiasis is a dangerous fungal infection affecting critically ill hospital patients. Current testing methods like blood cultures are slow and unreliable, so doctors are developing faster tests using DNA detection and biomarkers. A combination of new diagnostic tools and prompt treatment with antifungal medications is essential to improve survival rates and reduce complications from this serious infection.

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