Research Keyword: psychedelic microdosing

The therapeutic potential of microdosing psychedelics in depression

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This review examines whether taking very small doses of psychedelic drugs like LSD and psilocybin might help treat depression. While users report benefits and some studies show subtle positive effects on mood and thinking, scientists have not yet confirmed whether microdosing actually works as a depression treatment. More research with depressed patients is needed to understand if this approach is truly helpful and safe for regular use.

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Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls

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This study followed nearly 1000 people who microdose psilocybin (small regular doses of psilocybin mushrooms) and compared them to 180 people who don’t microdose over one month. Microdosers showed greater improvements in mood, depression, anxiety, and stress compared to the control group. Interestingly, when older adults combined psilocybin with lion’s mane mushrooms and niacin, they showed better improvements in motor control and speed. The effects were fairly consistent across different ages and genders, suggesting psilocybin microdosing may have real benefits for mental health.

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