Research Keyword: proteomics

Citric acid impairs type B trichothecene biosynthesis of Fusarium graminearum but enhances its growth and pigment biosynthesis: transcriptomic and proteomic analyses

Citric acid, a compound found in plant roots, has an interesting dual effect on a dangerous fungus called Fusarium graminearum that destroys grain crops worldwide. While citric acid helps the fungus grow better, it actually prevents the fungus from producing dangerous toxins called trichothecenes. This finding suggests that citric acid could potentially be used in farming to reduce the harmful toxins that contaminate wheat and corn while maintaining reasonable fungal control.

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Biochemical characteristics of extracts from proallergenic microfungi Erysiphe palczewskii and Erysiphe convolvuli

Researchers studied two types of fungi that cause powdery mildew on plants and can trigger allergies in people who breathe in their spores. They discovered that these fungi contain proteins that act as allergens, including special proteins that help fungi survive stress. The fungi also contain high levels of linoleic acid, a fatty acid that can increase inflammation in the body. This research helps scientists understand why these fungi can cause allergic reactions and could help develop better diagnostic tools for fungal allergies.

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Temporal and thermal optimization of trypsin digestion for the cryptococcal proteome

Scientists optimized how to digest proteins from a dangerous fungus called Cryptococcus neoformans to better identify all its proteins. They tested different time and temperature combinations for enzyme treatment and found that shorter digestion times (1 hour instead of overnight) work just as well. This finding makes protein analysis faster and easier for studying fungal infections and finding new treatments.

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Integrated Transcriptomic and Proteomic Analyses Reveal Molecular Mechanism of Response to Heat Shock in Morchella sextelata

Morels are delicious edible mushrooms, but growing them is challenging when temperatures get too high. Scientists studied two morel strains to understand how they respond to heat stress by examining their genes and proteins. They found that heat-tolerant strains activate special protective proteins and metabolic pathways, with one strain particularly good at activating a protein called Rsp5 that helps other protective proteins work better. These findings could help farmers grow better morels even as climate change makes temperatures warmer.

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Exploring the Critical Environmental Optima and Biotechnological Prospects of Fungal Fruiting Bodies

This research identifies the ideal growing conditions for fungal fruiting bodies like mushrooms, showing that temperature around 25°C, high humidity, and proper light exposure are key factors. The study reveals that exceeding these optimal conditions typically harms development more than staying slightly below them. Scientists discovered that fungal fruiting bodies have important uses in medicine, food production, and environmental cleanup, and new genetic technologies like CRISPR could improve cultivation methods for better yields and quality.

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Integrated Transcriptomic and Proteomic Analyses Reveal Molecular Mechanism of Response to Heat Shock in Morchella sextelata

Morels are delicious mushrooms that are difficult to grow because they are very sensitive to high temperatures. Scientists compared two different morel strains to understand why one variety can tolerate heat better than the other. By studying the genes and proteins expressed at normal and high temperatures, researchers discovered that the heat-tolerant strain activates specific protective mechanisms, particularly through a protein called Rsp5 that helps boost other protective proteins. This research provides valuable information for breeding morel varieties that can survive warmer growing conditions in the age of climate change.

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Growth conditions shape the proteome and diversity of Neurospora crassa extracellular vesicles

Scientists studied tiny particles called extracellular vesicles released by a common fungus (Neurospora crassa) under different growth conditions. Using advanced techniques, they identified hundreds of proteins within these vesicles and found that what the fungus eats and how long it grows significantly changes the types and amounts of proteins the vesicles carry. The findings reveal that fungi release different types of vesicles than previously thought, expanding our understanding of how cells communicate and transport materials.

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Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

Mushrooms are highly nutritious foods containing proteins as complete and high-quality as meat, with unique compounds that boost immunity, fight infections, and may help prevent diseases like cancer and diabetes. Different types of mushroom proteins have specific health benefits, from strengthening immune systems to lowering blood pressure and fighting viruses. Scientists are finding new ways to grow mushrooms and extract their proteins for use in sports nutrition, medicines, and fortified foods, making them increasingly valuable for human health and sustainability.

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Proteomic Analysis of Coprinopsis cinerea under Conditions of Horizontal and Perpendicular Gravity

Researchers studied how mushrooms respond to gravity using Coprinopsis cinerea, a common lab fungus. They found that while the fungal threads (mycelium) don’t respond to gravity, the fruiting bodies do by growing away from the direction gravity pulls. Using advanced protein analysis techniques, they identified 51 proteins that change their levels depending on gravity direction, suggesting that gravity response is connected to how mushrooms develop their fruiting bodies.

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Citric acid impairs type B trichothecene biosynthesis of Fusarium graminearum but enhances its growth and pigment biosynthesis: transcriptomic and proteomic analyses

Researchers discovered that citric acid, a natural acid found in plant roots and commonly used in agriculture, can reduce the production of dangerous mycotoxins called trichothecenes that contaminate wheat and corn crops. While citric acid surprisingly boosts the fungus’s growth and changes its color, it simultaneously shuts down the genes responsible for producing these toxic compounds. This discovery could help farmers use citric acid more strategically to prevent Fusarium head blight, a devastating crop disease, though care must be taken since it also promotes fungal growth.

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