Research Keyword: proteomics

Proteins from Edible Mushrooms: Nutritional Role and Contribution to Well-Being

Mushrooms are nutritional powerhouses containing as much high-quality protein as meat and soybeans, with complete amino acid profiles needed for human health. Beyond basic nutrition, mushroom proteins possess remarkable healing properties including anti-cancer, immune-boosting, and blood pressure-lowering effects. These sustainable proteins are increasingly used in food fortification, sports supplements, and therapeutic medicines. Growing mushrooms as mycelium or using novel cultivation methods makes protein production faster, more efficient, and environmentally friendly.

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Koumiss (Fermented Mare’s Milk) as a Functional Food: Bioactive Proteins, Peptides, and Future Perspectives

Koumiss is a fermented mare’s milk beverage consumed for centuries in Central Asia that offers unique health benefits. Unlike cow’s milk, mare’s milk is easier to digest, contains natural antimicrobial proteins, and when fermented develops thousands of bioactive peptides and beneficial bacteria. These compounds may help with cardiovascular health, gut function, and immune support, making koumiss a promising functional food for modern nutrition.

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Nature’s Own Pharmacy: Mushroom-Based Chemical Scaffolds and Their Therapeutic Implications

This comprehensive review explores how mushrooms can be used as natural medicines. Various mushroom species contain powerful compounds that can fight cancer, boost immunity, reduce inflammation, and treat infections. The paper details 15 important medicinal mushrooms and their therapeutic uses, showing that mushrooms are indeed a nature’s pharmacy with significant potential for treating many diseases.

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Insights into the evolution and mechanisms of response to heat stress by whole genome sequencing and comparative proteomics analysis of the domesticated edible mushroom Lepista sordida

Researchers sequenced the complete genome of Lepista sordida, a delicious edible mushroom valued for its health benefits, and studied how this mushroom responds to heat stress at the molecular level. Using advanced analysis techniques, they identified key proteins and signaling pathways that help the mushroom survive high temperatures. These findings can help farmers develop better-performing strains that are more resistant to heat, improving mushroom production.

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Advances in the Degradation of Polycyclic Aromatic Hydrocarbons by Yeasts: A Review

This review explores how yeasts, tiny single-celled fungi, can clean up environments contaminated with polycyclic aromatic hydrocarbons (PAHs) – harmful chemicals produced by car emissions, factories, and burning. These yeasts use special enzymes to break down these toxic compounds into less harmful substances, making them a promising natural solution for environmental cleanup. Scientists are also improving these yeasts through genetic engineering to make them even more effective at removing pollution.

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Functions of the Three Common Fungal Extracellular Membrane (CFEM) Domain-Containing Genes of Arthrobotrys flagrans in the Process of Nematode Trapping

Researchers studied how a fungus called Arthrobotrys flagrans catches and kills parasitic worms. They found that three genes containing a special protein domain called CFEM control how the fungus produces sticky traps and deadly proteins. By studying mutant fungi with these genes deleted or overexpressed, they discovered that these genes work together and can compensate for each other, helping explain how this fungus could be used as a natural pest control for harmful nematodes.

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Aspergillus fumigatus dsRNA virus promotes fungal fitness and pathogenicity in the mammalian host

Researchers discovered that a virus infecting the dangerous fungus Aspergillus fumigatus actually helps the fungus survive and cause worse infections in humans. By removing the virus from fungal strains, scientists found that the fungus became weaker and less able to cause disease in mice. Importantly, treating infected mice with an antiviral drug (ribavirin) reduced the viral load and helped the mice survive, suggesting a new approach to treating serious fungal infections.

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Comparative proteomics reveals the mechanism of cyclosporine production and mycelial growth in Tolypocladium inflatum affected by different carbon sources

Scientists studied how different sugar sources (fructose versus sucrose) affect the production of cyclosporine A, an important drug used to prevent organ rejection after transplants. Using advanced protein analysis techniques, they identified which proteins were more active in each sugar environment and discovered that fructose promotes drug production while sucrose promotes fungal growth. This research could help pharmaceutical companies produce cyclosporine more efficiently by identifying key proteins to enhance.

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Three new Pseudogymnoascus species (Pseudeurotiaceae, Thelebolales) described from Antarctic soils

Scientists discovered three new types of fungi living in Antarctic soils, naming them Pseudogymnoascus russus, P. irelandiae, and P. ramosus. Using genetic analysis and genome sequencing, researchers showed these fungi are adapted to survive in extremely cold conditions and represent previously unknown members of the Pseudogymnoascus family. This discovery adds to our understanding of Antarctic microbial life and suggests many more undescribed fungi may exist in Earth’s coldest environments.

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Production of β-Glucans by Pleurotus ostreatus: Cultivation and Genetic Background

Oyster mushrooms (Pleurotus ostreatus) are increasingly popular edible fungi that can grow on various waste materials like agricultural byproducts and food waste, making them both economical and environmentally friendly. These mushrooms produce valuable health-promoting compounds called β-glucans that have immune-boosting and antioxidant properties. Modern scientific techniques, including genetic analysis and artificial intelligence, are being used to optimize cultivation methods and increase production of these beneficial compounds. This sustainable approach to mushroom farming helps reduce waste while providing nutritious and medicinal food products.

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