Research Keyword: PROSPERO

Microbiota-based interventions for autism spectrum disorder: a systematic review of efficacy and clinical potential

This comprehensive review examines how modifications to gut bacteria through probiotics, prebiotics, synbiotics, and fecal transplants can help children with autism. The research found that while all these treatments showed some promise, fecal microbiota transplantation (FMT) produced the most consistent improvements in both autism-related behaviors and digestive symptoms. These microbiota-based approaches work through the gut-brain connection and were generally safe, making them potentially valuable additions to autism management strategies.

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The Potential of Mushroom Extracts to Improve Chemotherapy Efficacy in Cancer Cells: A Systematic Review

This systematic review examines how mushroom extracts can make chemotherapy more effective at treating cancer, particularly by helping overcome cancer cells’ resistance to drugs. Researchers found that various mushroom species contain compounds that work together with chemotherapy drugs to kill cancer cells more effectively through different cellular mechanisms. The results suggest mushroom extracts could be a promising natural complement to conventional cancer treatments, though more research is needed before they can be used clinically.

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