Research Keyword: prebiotics

Nutritional strategies in supporting immune checkpoint inhibitor, PI3K inhibitor, and tyrosine kinase inhibitor cancer therapies

This review examines how nutrition and food-based interventions can improve cancer treatment outcomes for patients receiving targeted cancer therapies. A Mediterranean-style diet with plenty of fiber (30-50g daily) appears beneficial for patients on immune checkpoint inhibitor therapies by promoting healthy gut bacteria that support immune function. The review also discusses promising research on fermented foods, specific bacterial supplements, mushroom extracts, and fasting approaches as complementary strategies to enhance cancer treatment effectiveness while reducing side effects.

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Unveiling roles of beneficial gut bacteria and optimal diets for health

Your gut bacteria are tiny living organisms that help digest food, support your immune system, and influence your overall health. Eating foods rich in fiber, fermented products like yogurt and kimchi, and colorful fruits and vegetables helps grow these beneficial bacteria. When your gut bacteria become unbalanced, it can lead to inflammation and various diseases, but eating the right foods can restore balance and improve your health.

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Effects of dietary Fibrafid as phytogenic supplementation in standard and nutrient-reduced diets on breast meat quality, carcass traits, histopathology, and feed efficiency in heat-stressed broilers

This research tested a plant-based feed additive called Fibrafid in broiler chickens raised in hot conditions. When included at 0.25% in their diet, Fibrafid improved meat quality by increasing its ability to retain moisture and enhancing tenderness, while also supporting growth even when using lower-nutrition diets. The additive maintained healthy intestines and improved feed efficiency, offering a practical and sustainable solution for poultry farmers in hot climates.

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The Effect of 2′-Fucosyllactose on Gut Health in Aged Mice

This research shows that 2′-fucosyllactose, a natural compound found in breast milk, can significantly improve gut health in older mice. The treatment strengthened the intestinal barrier, reduced harmful inflammation, and increased beneficial bacteria populations. These findings suggest that 2′-FL could be developed as a food supplement to help older people maintain better digestive and immune health.

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Effect of fiber-modified kombucha tea on gut microbiota in healthy population: A randomized controlled trial (RCT)

Researchers studied a kombucha tea drink enriched with fiber from chicory root in healthy adults over six weeks. The study found that people who consumed the fiber-enriched kombucha had lower triglyceride levels (blood fats) and beneficial changes in their gut bacteria, particularly an increase in Bifidobacterium, a bacteria known to support digestive health. These results suggest that this type of kombucha could be beneficial for metabolic and gut health, though more research is needed to confirm these benefits.

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The Role of Wolfiporia cocos (F. A. Wolf) Ryvarden and Gilb. Polysaccharides in Regulating the Gut Microbiota and Its Health Benefits

Wolfiporia cocos, a fungus used in traditional Chinese medicine for over 2000 years, contains polysaccharides that act as prebiotics to improve gut health. These polysaccharides promote the growth of beneficial bacteria while inhibiting harmful ones, increase production of healthy metabolites, and strengthen the intestinal barrier. By improving gut microbiota composition, these polysaccharides can help prevent and treat various diseases including obesity, diabetes, and inflammatory conditions.

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Prebiotics and Probiotics Supplementation in Pigs as a Model for Human Gut Health and Disease

Pigs are excellent models for studying human digestive health because their gut anatomy and function closely resemble humans. This review shows that prebiotics (special food compounds) and probiotics (beneficial bacteria) can improve gut health and strengthen the intestinal barrier in both healthy pigs and those with infections. These findings suggest that similar treatments might help prevent and treat digestive diseases in humans.

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Efficacy of prebiotic, probiotic and synbiotic administration in improving growth in children aged 0–59 months living in low- and middle-income countries: a systematic review and meta-analysis

This comprehensive review examined whether giving children special dietary supplements containing beneficial bacteria and their food sources (prebiotics, probiotics, or synbiotics) helps them grow better in low-income countries. The analysis of eight studies found that these supplements may help children gain weight, especially those who are malnourished, though the evidence remains limited. More research is needed to fully understand whether these supplements are truly effective for promoting healthy growth in young children.

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Effects of fiber sources with different solubilities on the growth performance, nutrient metabolism, antioxidant, immune capacity and intestinal health of meat geese

This study examined how different types of dietary fiber affect the health and growth of meat geese. Researchers compared three fiber sources with different levels of solubility: wheat bran (highly soluble), alfalfa meal (moderately soluble), and bamboo meal (low solubility). They found that the highly soluble fiber source improved growth, enhanced immune and antioxidant functions in the intestines, and promoted beneficial bacteria, making it the best choice for geese farming.

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Fungal β-Glucans Enhance Lactic Acid Bacteria Growth by Shortening Their Lag Phase and Increasing Growth Rate

Researchers tested whether extracts from common edible mushrooms like oyster and shiitake could help beneficial bacteria in the gut grow better. They found that these mushroom extracts, particularly their β-glucan components, helped probiotic bacteria start growing faster and grow more quickly. Importantly, the extracts did not help harmful bacteria grow, making them promising candidates for developing healthier food supplements that support gut health.

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