Research Keyword: population structure

Population structure in a fungal human pathogen is potentially linked to pathogenicity

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Aspergillus flavus is a common fungal infection found in both hospitals and the environment. Researchers studied the genetic makeup of 300 fungal samples from patients and the environment across multiple countries. They discovered that clinical isolates cluster into specific genetic groups, with one group containing most patient-derived samples. This finding suggests that certain genetic populations of this fungus may be better adapted to infecting humans than others.

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Population structure in a fungal human pathogen is potentially linked to pathogenicity

mycolabadmin

Researchers studied 300 strains of Aspergillus flavus, a fungus that causes serious infections in people and damages crops. They found that strains causing human infections are not randomly distributed but instead belong to specific genetic groups, particularly a newly identified group called population D. This discovery suggests that certain genetic traits make some strains more likely to infect humans, providing insights that could lead to better treatments and prevention strategies.

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Multilocus sequence typing of Candida albicans isolates from wild and farm animals from southern Italy

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Researchers in Italy studied a fungus called Candida albicans that can infect both humans and animals. They analyzed samples from chickens, wild boars, and lizards to understand how genetically similar these animal strains are to human infections. They found that animal strains are very similar to human strains, suggesting the fungus could be passed between animals and people. This research highlights the importance of monitoring fungal infections in animals to understand public health risks.

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Population structure in a fungal human pathogen is potentially linked to pathogenicity

mycolabadmin

A. flavus is a common fungal pathogen that causes serious infections in humans and damages crops. Researchers analyzed DNA from hundreds of fungal samples collected from both infected patients and environmental sources. They found that clinical isolates cluster into specific genetic groups, especially a newly identified group called population D that contains most of the disease-causing strains. This suggests that certain genetic variations make some fungal strains more likely to infect humans than others.

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Multilocus sequence typing of Candida albicans isolates from wild and farm animals from southern Italy

mycolabadmin

Researchers studied a fungal pathogen called Candida albicans found in farm and wild animals in Italy to understand how it spreads between animals and humans. They used genetic analysis to compare isolates from laying hens, wild boars, and lizards with samples from infected humans around the world. The results showed that animal isolates were genetically similar to human clinical samples, suggesting animals could serve as reservoirs for this infection. This research highlights the importance of monitoring fungal diseases in animal populations as part of understanding disease transmission between animals and people.

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