Research Keyword: polysaccharides

Multidisciplinary Integrative Medicine Approach for Cancer Patients: A Multicenter Retrospective Study

This study shows that when cancer patients use complementary treatments like mushroom supplements, vitamins, and probiotics alongside their cancer medications under doctor supervision, they experience fewer side effects and better quality of life. Almost 93% of patients had no side effects from these supplements, and many reported less fatigue and better overall wellness. The key finding is that patients should work with their medical team rather than self-prescribing these treatments to avoid dangerous interactions.

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Ultrasound-assisted development and characterization of novel polyphenol-loaded pullulan/trehalose composite films for fruit preservation

Researchers developed a new type of edible food wrap made from natural plant materials (tea polyphenols, pullulan, and trehalose) treated with ultrasound. This wrap is stronger, more protective against oxygen and moisture, and kills harmful bacteria like E. coli and Staphylococcus aureus. When used to wrap fresh apples and pears, it significantly extended their shelf life by reducing browning and decay.

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Exploring the Therapeutic Potential of Ganoderma lucidum in Cancer

Ganoderma lucidum, a mushroom used in traditional medicine for thousands of years, shows promise in fighting certain blood cancers like leukemia and lymphoma. The mushroom contains special compounds that can kill cancer cells in multiple ways—by triggering cancer cell death, boosting the immune system, and preventing cancer cell growth. While laboratory studies are very encouraging, more testing in humans is needed before it can be used as a standard cancer treatment.

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Medicinal Mushrooms: Bioactive Compounds, Use, and Clinical Trials

This comprehensive review examines how medicinal mushrooms contain natural compounds that can boost immune function, fight cancer cells, reduce inflammation, and protect nerve cells. Different mushroom species like reishi, shiitake, and maitake contain various active substances such as beta-glucans and triterpenes that work through multiple biological pathways. While laboratory and animal studies show promising results, more human clinical trials are needed to confirm effectiveness and establish safe dosing guidelines.

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The Effect of Green Extraction Technologies on the Chemical Composition of Medicinal Chaga Mushroom Extracts

Researchers compared three environmentally friendly methods for extracting beneficial compounds from Chaga mushrooms collected from Serbia and Mongolia. The study found that heating mushroom material with water under pressure (subcritical water extraction) was the most effective at extracting important compounds like glucans and phenols. These findings help the mushroom supplement industry choose the best extraction method based on which compounds they want to produce.

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Synergistic immuno-modulatory activity in human macrophages of a medicinal mushroom formulation consisting of Reishi, Shiitake and Maitake

Researchers studied a combination of three medicinal mushroom extracts to see if they work better together than separately. They tested this formula on human immune cells called macrophages and found that the combination was significantly more powerful at boosting immune responses than any single mushroom extract alone. This synergistic effect means the three mushrooms enhance each other’s immune-stimulating properties, suggesting this formula combination could have potential therapeutic benefits for immune support.

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The Possibility of Using Sulphur Shelf Fungus (Laetiporus sulphureus) in the Food Industry and in Medicine—A Review

Sulphur shelf fungus, known as ‘chicken of the woods,’ is a bright yellow mushroom that grows on tree trunks and has remarkable health benefits. Research shows it contains compounds with antioxidant, antibacterial, and anticancer properties, making it valuable for both food and medicine. The fungus can be cultivated relatively quickly and easily, and some countries already recognize it as safe for food use, potentially opening new applications in the food and pharmaceutical industries.

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Fungal Bioactive Compounds as Emerging Therapeutic Options for Age-Related Neurodegenerative Disorders

Mushrooms contain special compounds that may help protect our brains as we age. These fungal compounds fight inflammation, reduce harmful free radicals, and help clear out damaged cellular parts—all things that slow down brain aging and diseases like Alzheimer’s and Parkinson’s. While the research looks very promising in lab and animal studies, scientists still need to figure out how to make these compounds work better in the human body and prove they’re safe and effective in patients.

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Mushrooms-Rich Preparations on Wound Healing: From Nutritional to Medicinal Attributes

Mushrooms are nutritious foods that contain beneficial compounds like β-glucans and polysaccharides which can help wounds heal faster. These compounds work by activating immune cells and promoting collagen production, which are essential for skin repair. Research shows that mushroom extracts from species like Ganoderma lucidum and Hericium erinaceus can accelerate wound closure in experimental models and may benefit diabetic wound care and burn treatment.

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Therapeutic and Nutraceutical Potential of Sargassum Species: A Narrative Review

Sargassum is a type of ocean seaweed that has been used in traditional medicine for centuries and contains compounds that may help fight inflammation, oxidative stress, viruses, and bacteria. Scientists have discovered that different Sargassum species produce nearly 200 different bioactive compounds with potential health benefits ranging from reducing arthritis symptoms to supporting immune function. While Sargassum can accumulate harmful heavy metals like arsenic from seawater, researchers have developed effective cleaning methods to remove these contaminants while preserving the beneficial compounds. This makes Sargassum a promising sustainable source of natural medicines and health supplements.

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