Research Keyword: polysaccharide characterization

Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

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This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

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Formulation of functional noodles by adding Lentinus edodes mushroom powder: Physiochemical attributes, cellular mineral uptake and improved glycemic index

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Researchers developed a healthier version of noodles by adding shiitake mushroom powder at 4% concentration. These mushroom noodles had better nutritional content with more protein and minerals like iron and calcium that the body could actually absorb. Most importantly, the mushroom noodles caused a slower, more gradual rise in blood sugar compared to regular noodles, making them potentially beneficial for people managing diabetes.

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Interplay of precision therapeutics and MD study: Calocybe indica’s potentials against cervical cancer and its interaction with VEGF via octadecanoic acid

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Researchers discovered that an extract from the Calocybe indica mushroom effectively kills cervical cancer cells while leaving healthy immune cells unharmed. Using computer simulations, they identified that a compound in this mushroom called octadecanoic acid strongly binds to and blocks VEGF, a protein that helps cancer cells grow and spread. The extract reduced cancer cell movement by 50% and prevented cancer cells from forming colonies, suggesting this mushroom could become a new treatment option for cervical cancer.

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Bachu Mushroom Polysaccharide Alleviates Colonic Injury by Modulating the Gut Microbiota

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Researchers studied a polysaccharide extracted from Bachu mushrooms, a traditional medicinal fungus used in China, to treat inflammatory bowel disease in mice. The polysaccharide reduced inflammation by decreasing harmful inflammatory proteins and increasing beneficial bacteria in the gut. Treatment significantly improved disease symptoms and protected the colon from damage caused by chemical-induced colitis, suggesting this mushroom extract could potentially be developed into a natural treatment for inflammatory bowel disease.

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Chemical Characterization and In Vitro Antioxidant, Anti-Inflammatory, and Colon Cancer-Preventive Potential of a Polysaccharide Fraction from Macrolepiota procera

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Researchers isolated special sugar compounds called polysaccharides from parasol mushrooms and tested their health benefits. These compounds were found to fight free radicals that damage cells, reduce inflammation in the body, and specifically kill colon cancer cells while leaving healthy cells unharmed. The study suggests that parasol mushrooms could be developed into health supplements or functional foods to help prevent cancer and improve overall health.

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