Research Keyword: polysaccharide biosynthesis

Exploring the Mechanisms of Amino Acid and Bioactive Constituent Formation During Fruiting Body Development in Lyophyllum decastes by Metabolomic and Transcriptomic Analyses

mycolabadmin

This research study examined how Lyophyllum decastes mushrooms develop and accumulate their valuable nutrients and flavor compounds. Scientists found that amino acids and polysaccharides reach their highest levels when the mushroom is mature, ready for harvesting. By analyzing the genes and chemical changes during mushroom growth, researchers identified the specific pathways responsible for producing these beneficial compounds. This knowledge helps improve mushroom cultivation and confirms its value as a healthy functional food.

Read More »

Revitalization of the Endophytic Fungus Acremonium sp. MEP2000 and Its Impact on the Growth and Accumulation of Bioactive Compounds in Inonotus obliquus

mycolabadmin

Researchers successfully revived a beneficial fungus called Acremonium sp. MEP2000 that had lost its effectiveness through repeated cultivation by adding birch bark powder and medicinal mushroom powder to its growth medium. When used to treat the medicinal fungus Inonotus obliquus (chaga), this revitalized fungal culture dramatically improved the growth and production of healthy bioactive compounds like polysaccharides and triterpenoids. This breakthrough offers a practical solution for large-scale production of medicinal fungi with enhanced therapeutic potential for treating cancer, diabetes, and inflammatory conditions.

Read More »

Kre6-dependent β-1,6-glucan biosynthesis only occurs in the conidium of Aspergillus fumigatus

mycolabadmin

Researchers discovered that a specific sugar compound called β-1,6-glucan is found in the spore-like reproductive structures (conidia) of the fungus Aspergillus fumigatus but not in its growing filaments (mycelium). Using advanced nuclear magnetic resonance technology, they identified the KRE6 gene as responsible for making this sugar and found that removing this gene makes the fungus more vulnerable to certain chemicals that damage fungal cell walls.

Read More »

Comparative transcriptome analysis reveals the genetic basis underlying the biosynthesis of polysaccharides in Hericium erinaceus

mycolabadmin

Researchers studied six different strains of lion’s mane mushrooms to understand how they produce beneficial compounds called polysaccharides. Using advanced genetic analysis, they identified thirteen key genes responsible for making these health-promoting molecules. The study found that a strain called PZH-05 produced the most polysaccharides, and its genes were more active than in other strains. This research helps explain why lion’s mane mushrooms are effective for boosting immunity, fighting cancer, and managing blood sugar.

Read More »

Cgm1 is a β-galactoside α-(1 → 4)-mannosyltransferase involved in the biosynthesis of capsular glucuronoxylomannogalactan in Cryptococcus neoformans

mycolabadmin

Researchers identified a new fungal enzyme called Cgm1 that helps the fungus Cryptococcus neoformans build its protective capsule, which allows it to evade the immune system. When this enzyme is disabled, the fungus becomes weak at body temperature and triggers a stronger immune response in infected mice. Since humans and plants don’t have this enzyme, it could be a promising target for developing new antifungal medications.

Read More »

Exploring the Mechanisms of Amino Acid and Bioactive Constituent Formation During Fruiting Body Development in Lyophyllum decastes by Metabolomic and Transcriptomic Analyses

mycolabadmin

This study examined how Lyophyllum decastes mushrooms develop and build up their nutritious compounds. Researchers tracked amino acids and polysaccharides across four growth stages and identified which genes control their production. The mature mushrooms contained the highest levels of beneficial compounds, with amino acids reaching 45,107.39 μg/g and polysaccharides at 13.66 mg/g. These findings help explain why these mushrooms are nutritious and suggest ways to grow them better for maximum health benefits.

Read More »
Scroll to Top