Research Keyword: polyamines

Exogenous L-Arginine Enhances Pathogenicity of Alternaria alternata on Kiwifruit by Regulating Metabolisms of Nitric Oxide, Polyamines, Reactive Oxygen Species (ROS), and Cell Wall Modification

Researchers discovered that a specific nutrient called L-arginine paradoxically makes a fungus that causes black spot on kiwifruit more dangerous at low concentrations. The fungus uses this amino acid to trigger multiple survival mechanisms including producing protective molecules and enzymes that break down plant cell walls. However, at higher concentrations, L-arginine actually inhibits the fungus, suggesting it could be used as part of a disease control strategy.

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Polyamine Induction of Secondary Metabolite Biosynthetic Genes in Fungi Is Mediated by Global Regulator LaeA and α-NAC Transcriptional Coactivator: Connection to Epigenetic Modification of Histones

Polyamines are natural compounds that act like chemical switches controlling how fungi produce useful medicines like antibiotics and statins. These molecules work by attaching to DNA and modifying histone proteins, which turns on or off the genes responsible for making pharmaceutical compounds. This research reveals that understanding polyamine control could help scientists increase antibiotic production and make plants more resistant to fungal diseases.

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