Research Keyword: PLGA nanoparticles

Synbiotic yogurt with nanoparticle entrapped rice straw hemicellulose for immediate probiotic support and prebiotic delivery

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Scientists created a new type of yogurt that contains beneficial bacteria and special prebiotics from rice straw. The innovation uses tiny nanoparticles to protect some of the prebiotics so they reach your gut intact, while free prebiotics immediately feed the beneficial bacteria in the yogurt during storage. This dual-delivery approach keeps the yogurt fresher longer while ensuring you get maximum health benefits for your digestive system.

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Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

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Researchers developed special nanoparticles that can cross the protective barrier surrounding the brain by using a protein from a fungal infection. These nanoparticles are loaded with an antifungal drug and can effectively treat cryptococcal brain infections in laboratory tests. This approach offers a new way to deliver medicines to the brain without invasive procedures, potentially helping patients with serious brain infections that are currently difficult to treat.

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Conjugation of a Cryptococcus neoformans-derived metalloprotease to antifungal-loaded PLGA nanoparticles treats neural cryptococcosis in an in vitro model

mycolabadmin

Researchers developed tiny nanoparticle carriers coated with a fungal enzyme that helps them cross the protective barrier around the brain. These particles were loaded with an antifungal drug to treat brain infections caused by Cryptococcus neoformans. In laboratory tests, the Mpr1-coated particles successfully penetrated the blood-brain barrier better than regular nanoparticles and were more effective at killing the fungal cells.

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