Research Keyword: plasma membrane

Lomasomes and Other Fungal Plasma Membrane Macroinvaginations Have a Tubular and Lamellar Genesis

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Scientists studied mushroom cells to understand structures called lomasomes that form at the cell membrane surface. Using advanced microscopy techniques, they discovered these structures are made of tiny tubes and layers that can fold and swell into different shapes. These findings help explain how fungal cells that decompose wood organize their membranes and may be involved in how cells take in materials from their surroundings.

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Beyond division and morphogenesis: Considering the emerging roles of septins in plasma membrane homeostasis and cell wall integrity in human fungal pathogens

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Septins are protein structures inside fungal cells that help them divide and maintain their outer layers. This review explains how these proteins play crucial roles in fungal infections by helping pathogens survive stress conditions and respond to host defenses. By understanding how septins work, scientists might develop new antifungal medications that target these proteins to fight stubborn fungal infections.

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Biophysical modeling of membrane curvature generation and curvature sensing by the glycocalyx

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The glycocalyx is a sugar-rich layer covering cells that helps cells interact and defend against infection. This research explains how the structure and density of glycocalyx molecules can physically bend and shape cell membranes by creating steric pressures. Scientists developed a mathematical model and confirmed through experiments that thicker glycocalyx layers generate more membrane curvature, and that these molecules preferentially accumulate in highly curved regions, suggesting they can sense membrane shape.

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