Research Keyword: phytochemical screening

In vitro assessment of multipotential therapeutic importance of Hericium erinaceus mushroom extracts using different solvents

This research examined how Lion’s Mane mushroom extracts made with different liquids can fight infections and oxidative damage. The water-based extract was best at preventing viruses and free radical damage, while the ethyl acetate extract worked best against bacteria and fungi. The study identified 16 beneficial compounds in the mushroom and suggests it could be used as a daily supplement to protect against infections and oxidative stress.

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In vitro antifungal activity of plant extracts against fungal pathogens of onion (Allium cepa L.) and red pepper (Capsicum annum L.) in selected districts of Western Hararghe, Ethiopia

Onion and pepper farmers in Ethiopia lose significant crops to fungal diseases, and chemical fungicides are expensive and harmful. This study tested plant extracts from garlic, neem, and African wintersweet against disease-causing fungi. Acokanthera schimperi (African wintersweet) was most effective at stopping fungal growth, offering farmers an affordable, natural, and environmentally safe alternative to chemical fungicides.

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Diversity and bioprospecting activities of endophytic Fungi associated with different Egyptian medicinal plants

Scientists studied fungi that live inside Egyptian medicinal plants and found that one type called Aspergillus terreus produces compounds with powerful healing properties. These compounds can fight harmful bacteria, reduce oxidative damage, and even kill cancer cells while being safe for normal cells. This discovery suggests that fungi living in medicinal plants could be valuable sources of new medicines, offering hope for developing new treatments for infections and cancer.

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From Mushrooms to Molecules: Exploring Depsidones in Ganoderma lucidum for Antioxidant and Anticancer Applications

This research examined reishi mushroom (Ganoderma lucidum), a traditional medicinal fungus, to find rare compounds called depsidones with potential cancer-fighting properties. Scientists extracted these compounds using different solvents and tested them against four types of cancer cells (liver, colon, breast, and lung cancer), finding that they successfully killed cancer cells while being safe to normal cells. Using advanced chemical analysis and computer modeling, they identified nine new depsidone compounds in reishi and showed how these compounds could bind to cancer-related proteins to stop tumor growth.

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Inhibitive effect of Urginea epigea methanolic extract and silver/zinc oxide nanoparticles on Aspergillus and aflatoxin production

Scientists tested a plant called Urginea epigea and special tiny particles made of silver and zinc to stop a dangerous fungus called Aspergillus flavus from growing and producing aflatoxins, which are harmful poisons found in food. When used at the right concentration, the plant extract completely stopped the fungus from growing. The treatment worked by turning off the fungus’s ability to make the poison by reducing the activity of specific genes. This natural approach could offer a safer alternative to chemical fungicides for protecting our food supply.

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Evaluating the antioxidant, anti-inflammatory, and neuroprotective potential of fruiting body and mycelium extracts from edible yellow morel (Morchella esculenta L. Pers.)

This study examined morel mushrooms from Pakistan to see if they could help treat Alzheimer’s disease and related brain conditions. Researchers tested both the fruiting bodies and the root-like mycelia of Morchella esculenta mushrooms for their ability to fight oxidative stress, reduce inflammation, and inhibit an enzyme that breaks down acetylcholine, a brain chemical important for memory. The results showed that morel extracts, especially from fruiting bodies collected in certain regions, worked as well as or better than conventional medications, suggesting these common edible mushrooms could be developed into treatments for neurodegenerative diseases.

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Phytochemical Profile and Antimicrobial Activities of Edible Mushroom Termitomyces striatus

Researchers studied an edible mushroom called Termitomyces striatus traditionally consumed in Africa and Asia to understand its disease-fighting properties. They found that extracts from this mushroom contain beneficial compounds that can kill harmful bacteria and fungi in laboratory tests. The dichloromethane extract was the most effective, showing strong activity against multiple disease-causing bacteria and the yeast Candida albicans. This suggests the mushroom could potentially be developed into new natural antimicrobial treatments.

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