phylogenomics – Page 3

Large-scale phylogenomic insights into the evolution of the Hymenochaetales

mycolabadmin

This study examined the evolutionary history of over 1,200 species of wood-decomposing and disease-causing fungi called Hymenochaetales using genetic analysis of 171 fungal genomes. The researchers found that these fungi likely originated in temperate regions of Asia during the age of dinosaurs and gradually spread worldwide, changing their physical forms as they diversified. The research provides important insights into how major groups of fungi evolved and adapted over millions of years.

Phylogenomic, Morphological, and Phylogenetic Evidence Reveals Five New Species and Two New Host Records of Nectriaceae (Hypocreales) from China

mycolabadmin

Scientists in China discovered five new species of fungi from the Fusarium and Neocosmospora groups, which can affect plants and, in rare cases, humans. These fungi were found in various environments including plant leaves, insects, and other fungi. The researchers used advanced DNA analysis and genetic sequencing techniques to identify these new species and clarify how they relate to each other evolutionarily.

Tracing the Origin and Evolution of the Fungal Mycophenolic Acid Biosynthesis Pathway

mycolabadmin

Mycophenolic acid is an important drug that helps transplant patients by preventing their immune systems from rejecting new organs. Scientists studied the genes that fungi use to make this drug and found it in several fungal species. They discovered that this ability to produce the drug evolved a long time ago in fungi but was lost in most species over time, remaining only in a few special fungi.

Large-scale phylogenomic insights into the evolution of the Hymenochaetales

mycolabadmin

Scientists studied the evolutionary history of a large group of wood-decaying fungi called Hymenochaetales using genetic information from 171 different fungal species. They discovered that these fungi likely originated in temperate regions of Asia around 167 million years ago and gradually spread worldwide. The research reveals how these fungi changed shape and form over millions of years and shows they are still diversifying today.

Genome sequencing and analysis of isolates of Cytospora sorbicola and Cytospora plurivora associated with almond and peach canker

mycolabadmin

Scientists have sequenced the complete genetic code of two fungal species that cause destructive canker diseases in almond and peach trees. These fungi are difficult to control once they infect trees, and developing disease-resistant plant varieties is the best approach to protect orchards. The genetic information from this study will help researchers understand how these fungi cause disease and develop better strategies to breed resistant fruit trees.

Contamination of fungal genomes of Onygenaceae (Phylum Ascomycota) in public databases: incidence, detection, and impact

mycolabadmin

Scientists found that many fungal genome sequences stored in public databases contain unwanted bacterial DNA that can interfere with research results. They developed a method to identify and remove this contamination using related high-quality fungal genomes as reference. After cleaning four contaminated genomes, the quality improved significantly and the contamination dropped from 5-12% to below 3%, demonstrating that careful screening is essential for reliable genetic research.

Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight

mycolabadmin

This research examines a dangerous fungus called Calonectria eucalypti that destroys eucalyptus trees worldwide. Scientists sequenced the fungus’s complete genetic code and tracked which genes turn on during infection, discovering that the pathogen uses different sets of genes at different stages of infection. By identifying key virulence genes and understanding how the fungus attacks plant cells, this research provides a foundation for developing better ways to prevent and manage eucalyptus leaf blight disease.

The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

mycolabadmin

Researchers sequenced the complete genome of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in Chinese traditional medicine for treating parasites and digestive issues. The study reveals the mushroom’s genetic makeup, including 15,847 genes and over 3 million methylation marks that may control gene expression. They identified 67 gene clusters that could produce medicinal compounds and 521 enzymes for breaking down organic matter. This genetic blueprint will help scientists understand how to cultivate this threatened species sustainably and develop its health benefits.

The First Whole Genome Sequence and Methylation Profile of Gerronema lapidescens QL01

mycolabadmin

Scientists have sequenced the complete genetic code of Lei Wan (Gerronema lapidescens), a medicinal mushroom used in traditional Chinese medicine for treating parasitic infections and digestive problems. The research revealed how this mushroom produces beneficial compounds and how its genes are regulated through a process called methylation. This information could help develop better ways to cultivate this increasingly rare mushroom sustainably rather than harvesting it from the wild, making it available for future medical research and treatment.

Phylogenomic, Morphological, and Phylogenetic Evidence Reveals Five New Species and Two New Host Records of Nectriaceae (Hypocreales) from China

mycolabadmin

Researchers identified five new species of fusarioid fungi (Fusarium and Neocosmospora) found in China by combining morphological observations with advanced genetic analysis of 4,941 genes. These fungi are important because they can be beneficial endophytes, harmless decomposers, or disease-causing pathogens. The study used modern genomic techniques to clearly distinguish between closely related species and confirmed fundamental differences between the two main genera. These findings will help scientists better identify and manage diseases caused by these fungi in agriculture and medicine.

Research Keyword: phylogenomics