Lion’s Mane mushrooms grown on a special mixture of agricultural waste materials showed the best antioxidant properties in this study. Researchers found that combining sawdust, wheat straw, bagasse, rice bran, and corn flour created the ideal growing environment. The mushrooms produced high levels of protective compounds called phenolics and flavonoids that help fight harmful free radicals in the body. This research shows how we can turn agricultural waste into valuable medicinal mushrooms with strong health benefits.