Research Keyword: PCR analysis

A Unique Case of Fungal Endometritis Caused by Aspergillus quadrilineatus in an Immunocompetent Woman and Literature Review

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A 64-year-old woman experienced persistent vaginal bleeding for three months, which was found to be caused by a rare fungal infection (Aspergillus quadrilineatus) in her uterus. Through tissue examination and molecular testing, doctors identified the fungus and found it was sensitive to common antifungal medications. The patient was successfully treated with antifungal medication combined with surgical cleaning of the uterus, making a complete recovery. This case highlights that fungal infections should be considered when patients have abnormal vaginal bleeding, even if they appear otherwise healthy.

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Inhibitive effect of Urginea epigea methanolic extract and silver/zinc oxide nanoparticles on Aspergillus and aflatoxin production

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Researchers tested whether a plant called Urginea epigea could stop the growth of a dangerous fungus (Aspergillus flavus) that produces aflatoxins, which can harm humans and animals. The plant extract completely stopped fungus growth at high concentrations and significantly reduced the production of toxins by turning off the genes responsible for toxin production. This suggests that plant-based treatments could offer a natural alternative to synthetic chemical fungicides for protecting food from contamination.

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Acute fungal endometritis in women with abnormal uterine bleeding: Clinical and microbiological insights

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Women with persistent abnormal uterine bleeding often undergo extensive testing without finding a cause. This study discovered that fungal infections, caused by Candida species, may be responsible for about 12% of such cases. The researchers found that direct sampling of the uterine lining is essential for diagnosis since surface vaginal cultures miss these infections. Treatment with an antifungal medication called voriconazole combined with surgical cleaning of the uterus proved effective in resolving the condition.

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