Research Keyword: pathogenic fungus

Streptomyces-Based Bioformulation to Control Wilt of Morchella sextelata Caused by Pestalotiopsis trachicarpicola

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Morel mushrooms are delicious and nutritious but are threatened by a fungal disease that can destroy up to 80% of crops. Scientists discovered that two beneficial bacteria species (Streptomyces) from morel soil produce compounds that kill the disease-causing fungus. When applied to morel fields, these beneficial bacteria not only prevented the disease but also increased mushroom yields by about 30% compared to untreated crops, offering a natural and sustainable solution for morel farmers.

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Acidic pH Modulates Cell Wall and Melanization in Paracoccidioides brasiliensis, Affecting Macrophage Interaction

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A dangerous fungal infection called paracoccidioidomycosis affects people in Latin America. Researchers found that when this fungus encounters acidic conditions similar to those inside immune cells in the body, it protects itself by producing a dark pigment called melanin and changing its cell surface. These changes help the fungus hide from the immune system and reduce the ability of immune cells called macrophages to attack and destroy it.

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Whole-genome sequencing of global forest pathogen Diplodia sapinea causing pine shoot blight

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Scientists have sequenced the complete genome of Diplodia sapinea, a fungus that causes serious disease in pine trees worldwide. This fungus normally lives harmlessly inside healthy pine trees but becomes dangerous during stressful conditions like droughts or storms. The new genome information will help scientists understand how this pathogen works and develop better ways to prevent and control the disease in forests.

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Co-transformation of Aspergillus fumigatus: a simple and efficient strategy for gene editing without linking selectable markers

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Scientists have developed a new technique for editing genes in a dangerous fungal pathogen called Aspergillus fumigatus. Instead of permanently attaching antibiotic resistance markers to the target genes (which can interfere with normal gene function), they use a clever strategy of introducing two different DNA pieces simultaneously. One piece makes the desired gene edit while the second introduces a resistance marker to a completely different location in the genome. This approach is simple, inexpensive, and works about 11% of the time, making it practical for identifying successfully edited strains.

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