Research Keyword: pathogenic bacteria

The role of Micro-biome engineering in enhancing Food safety and quality

Microbiome engineering uses advanced biotechnology to strategically modify helpful bacteria in food to make it safer and higher quality. By using tools like CRISPR gene editing and engineering beneficial probiotics, scientists can prevent food spoilage, reduce harmful bacteria, improve nutrition, and create better-tasting foods. These innovations could reduce reliance on synthetic preservatives and chemicals while addressing global food safety challenges and helping combat malnutrition.

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Mathematical Modeling of Escherichia coli and Lactobacillus acidophilus Growth Based on Experimental Mixed Batch Cultivation

Researchers studied how two common bacteria – beneficial Lactobacillus acidophilus and harmful E. coli – interact when grown together in laboratory cultures. Using advanced flow cytometry techniques and computer models that track individual bacterial generations, they found that L. acidophilus naturally inhibits E. coli growth through production of lactic acid and antimicrobial compounds. This research provides insights useful for developing probiotic treatments and understanding food fermentation processes.

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Comprehensive whole metagenomics analysis uncovers microbial community and resistome variability across anthropogenically contaminated soils in urban and suburban areas of Tamil Nadu, India

Researchers analyzed soil samples from eight polluted locations in India to understand how microbes adapt to heavy metal and chemical contamination. They discovered that contaminated soils harbor many bacteria with antibiotic resistance genes and genes that help them survive toxic metals. The most common resistance mechanism was through special pumps that bacteria use to expel antibiotics. This research highlights how polluted environments become reservoirs of antibiotic-resistant bacteria, emphasizing the need for targeted cleanup strategies to protect human and environmental health.

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Pathogen Identification, Antagonistic Microbe Screening, and Biocontrol Strategies for Aconitum carmichaelii Root Rot

Aconitum carmichaelii is a traditional Chinese medicinal plant that has become increasingly prone to root rot disease due to continuous farming in Yunnan. Researchers identified multiple disease-causing pathogens and discovered that beneficial bacteria called Bacillus can both fight these pathogens and improve plant health. One particularly effective strain enhanced soil quality and increased the plant’s natural defenses, achieving over 50% disease control without chemical pesticides.

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Antibiofilm activity and bioactive phenolic compounds of ethanol extract from the Hericium erinaceus basidiome

Researchers tested a lion’s mane mushroom extract for its ability to stop harmful bacteria from forming protective biofilms that make infections harder to treat. The extract showed strong activity against Proteus mirabilis bacteria, reducing biofilm formation by over 78%. The antibiofilm power comes mainly from two phenolic compounds: protocatechuic acid and p-coumaric acid. These findings suggest lion’s mane mushroom could be developed into natural supplements or food preservatives to prevent bacterial contamination.

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Atypical Cutaneous Manifestation of Mycosis Fungoides: A Case Report

A 68-year-old woman with mycosis fungoides, a rare skin cancer, developed severe infected lesions after swimming in the ocean. Her wounds were infected with four different types of bacteria that had not been previously reported together in this disease. She was treated with antibiotics and improved, highlighting the importance of patients with this condition avoiding water exposure and maintaining regular medical care.

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Differential composition of the pulmonary microbiome in HIV-positive versus HIV-negative patients with Pneumocystis jirovecii

This study compared lung infections in HIV-positive and HIV-negative patients who both had Pneumocystis jirovecii. Researchers found that HIV-positive patients had more diverse microorganisms in their lungs, particularly viruses, yet generally did better. HIV-negative patients had fewer types of microorganisms but worse outcomes. The findings suggest that the way a person’s immune system is weakened matters more than just having many germs present.

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Mycelial Beehives of HIVEOPOLIS: Designing and Building Therapeutic Inner Nest Environments for Honeybees

Scientists created experimental beehives made from living mushroom mycelium (the root structure of mushrooms) combined with 3D-printed scaffolds. These hives are designed to keep bees warmer while providing natural antimicrobial compounds that protect them from diseases. The research combines digital design technology with biology to create homes that mimic the natural tree cavities where wild honeybees live, potentially making them healthier and more resilient to climate change and diseases.

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Strain-specific effects of Desulfovibrio on neurodegeneration and oxidative stress in a Caenorhabditis elegans PD model

This research shows that different strains of bacteria called Desulfovibrio have very different effects on brain health. When scientists exposed worms to six different strains, they found that environmental strains actually protected against Parkinson’s-like symptoms, while strains from human patients and animals caused more damage. The worms strongly preferred to eat the environmental strains, suggesting they could sense which bacteria were harmful. This highlights how the type of bacteria in our gut matters just as much as the total amount.

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Nutritional contents and antimicrobial activity of the culinary-medicinal mushroom Leccinum scabrum

This study examined the health benefits of Leccinum scabrum, a mushroom used both as food and medicine. Researchers tested extracts from this mushroom against harmful bacteria and found they were very effective at stopping bacterial growth. The extracts were created using two different methods and both worked well, suggesting this mushroom could have practical antimicrobial applications.

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