Research Keyword: pathogen virulence

Intraspecies sequence-graph analysis of the Phytophthora theobromicola genome reveals a dynamic structure and variable effector repertoires

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Researchers sequenced the genome of Phytophthora theobromicola, a newly discovered fungal pathogen that causes serious cacao plant disease. They found the pathogen’s genome is highly variable among different isolates and contains many genes that help it attack cacao plants. By studying which of these harmful genes are active during infection, they identified specific virulence factors unique to this cacao pathogen that could be important targets for future disease control strategies.

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CBC Complex Regulates Hyphal Growth, Sclerotial Quantity, and Pathogenicity in the Necrotrophic Fungus Botrytis cinerea

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Scientists studied how two proteins (BcCbp20 and BcCbp80) work together in gray mold fungus, which destroys crops worldwide. These proteins control how the fungus grows, makes spores, forms long-term survival structures, and causes disease. The findings show that BcCbp80 is more important for growth and infection, while BcCbp20 helps the fungus survive stress. Understanding these proteins could help develop new antifungal treatments.

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Editorial: Unraveling pathogen-plant-microbiome interactions in horticultural crops through omics approaches

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This editorial presents a collection of research on how diseases affect valuable crops like tomatoes, tea, and potatoes. Scientists used advanced genetic and molecular techniques to understand how pathogens infect plants and how the beneficial microbes around plant roots can help fight disease. The studies suggest that managing crop diseases sustainably requires understanding the complex interactions between pathogens, plants, and their microbial communities.

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Effects of simulated microgravity on biological features and virulence of the fungal pathogen Cryptococcus neoformans

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Scientists studied how a dangerous fungus called Cryptococcus neoformans behaves in space-like conditions. They found that in simulated microgravity, this fungus becomes more dangerous by developing thicker protective capsules, producing more protective pigment, and becoming more deadly to organisms in laboratory models. This research is important because astronauts in space have weaker immune systems, making them vulnerable to infections from fungi that may have adapted to thrive in space environments.

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A non-classical PUF family protein in oomycetes functions as a pre-rRNA processing regulator and a target for RNAi-based disease control

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Scientists discovered a critical protein called Puf4 in harmful water mold pathogens (oomycetes) that damage crops. When they removed this protein from the pathogens, the organisms grew poorly and couldn’t infect plants effectively. They also developed a new method to deliver therapeutic RNA directly through zoospores (swimming spores) that successfully reduced disease in infected plants, offering an eco-friendly alternative to traditional pesticides.

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Integrated genome and transcriptome analysis reveals pathogenic mechanisms of Calonectria eucalypti in Eucalyptus leaf blight

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This research examines a dangerous fungus called Calonectria eucalypti that destroys eucalyptus trees worldwide. Scientists sequenced the fungus’s complete genetic code and tracked which genes turn on during infection, discovering that the pathogen uses different sets of genes at different stages of infection. By identifying key virulence genes and understanding how the fungus attacks plant cells, this research provides a foundation for developing better ways to prevent and manage eucalyptus leaf blight disease.

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