Research Keyword: pathogen-host interaction

Post-Harvest Quality Changes and Molecular Responses of Epidermal Wax in ‘Munage’ Grapes with Botrytis cinerea Infection

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‘Munage’ grapes from Xinjiang are susceptible to a fungus called Botrytis cinerea that causes gray mold during storage. The fungus dissolves the protective waxy coating on the grape surface, leading to faster deterioration. The study identified specific genes and proteins that control wax production, which could help scientists develop better storage methods and disease prevention strategies to keep grapes fresher longer.

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The dimorphic fungus Talaromyces marneffei: An opportunistic killer in Southeast Asia

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Talaromyces marneffei is a dangerous fungus found in Southeast Asian soils that causes serious lung infections when people breathe in its spores. The fungus has a clever trick: it transforms into different forms depending on temperature and hides inside immune cells by tricking them. People with weak immune systems, particularly those with advanced HIV/AIDS or certain genetic conditions, are most vulnerable to severe disease.

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Integrated Transcriptomics–Proteomics Analysis Reveals the Response Mechanism of Morchella sextelata to Pseudodiploöspora longispora Infection

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White mold disease is a major problem for morel mushroom farmers in China. Researchers identified the fungus causing this disease and studied how morel cells defend themselves. Using advanced molecular techniques, they found that morel cells respond to infection by changing their cell membranes and walls, and by activating protective proteins that fight oxidative stress. This research helps explain how the disease damages morels and could lead to developing stronger, disease-resistant mushroom varieties.

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Standardization of challenge inoculation protocols for artificial infection of Fusarium acutatum and Fusarium falciforme causing basal rot of onion

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This research develops standardized methods for infecting onion bulbs with fungal diseases in laboratory settings to test which onion varieties can resist the infection. Two Fusarium fungi species that cause onion basal rot were tested using five different inoculation techniques. The cotton swab method proved most effective and practical for screening large numbers of onion plants. These findings will help farmers and plant breeders develop onion varieties resistant to these economically important diseases.

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Deubiquitinase Ubp5 is essential for pulmonary immune evasion and hematogenous dissemination of Cryptococcus neoformans

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This study shows that removing a fungal enzyme called Ubp5 from Cryptococcus neoformans significantly weakens the fungus and allows the body’s immune system to fight the infection more effectively. The fungus without Ubp5 loses its ability to hide from the immune system, triggering stronger protective immune responses including more T cells and beneficial inflammatory signals. This research suggests that targeting Ubp5 could be a promising strategy to help treat cryptococcal infections by enhancing the body’s natural defense mechanisms.

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