Research Keyword: pathogen-associated molecular patterns (PAMPs)

Bioinspired nano-architected chitosan-β-glucan nanocomposite as an elicitor for disease management sustainably

Scientists created tiny engineered particles made from chitosan and β-glucan that act like alarm signals to boost plants’ natural defenses against a destructive soil fungus called Sclerotium rolfsii. These nano-particles are extremely effective at just 220-240 parts per million, far more powerful than conventional fungicides which require 2000 ppm. The particles work by damaging the fungus’s cells directly while also triggering the plant’s immune system, offering farmers a sustainable alternative to chemical pesticides.

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Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

Scientists studied three types of dangerous fungi that cause serious infections in people with weak immune systems. They looked at the outer coating of these fungi cells, which is what the body’s immune system first encounters during infection. They found that this coating contains multiple types of sugar-like substances that trigger strong inflammatory responses in immune cells. Understanding these fungi better could help develop better treatments for these serious infections.

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Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

Mucormycosis is a serious fungal infection that primarily affects people with weak immune systems and carries high mortality rates. Researchers studied three common mucormycosis-causing fungi to understand how their outer cell layers interact with the human immune system. They found that all three fungi trigger strong inflammatory responses, which may explain why the disease is so damaging. This research helps us better understand how these infections work and could lead to improved treatments or vaccines.

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