Research Keyword: PAMP

Pathogenic mucorales: Deciphering their cell wall polysaccharidome and immunostimulatory potential

Mucormycosis is a dangerous fungal infection that kills many immunocompromised patients. Researchers analyzed the outer layer (cell wall) of three common disease-causing fungi and discovered that their surfaces contain sugar-like molecules that trigger strong inflammatory responses from the immune system. This excessive inflammation may actually contribute to the disease’s severity, suggesting that controlling inflammation alongside antifungal treatment might improve patient outcomes.

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Edible Mushrooms and Beta-Glucans: Impact on Human Health

Mushrooms contain compounds called β-glucans that can help boost your immune system and reduce inflammation. These compounds show promise in cancer treatment when combined with conventional therapies and may help fight infections. While mushrooms have long been used in traditional medicine, modern research is confirming their health benefits and understanding how they work in the body.

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The Prognostic Value of (1→3)-β-D-Glucan in COVID-19 Patients with and Without Secondary Fungal Disease

During COVID-19, patients in intensive care sometimes develop dangerous fungal infections. Doctors use a blood test to measure a fungal marker called BDG to help diagnose these infections. This study found that even without confirmed fungal infection, high BDG levels predicted who would not survive, but giving antifungal medications improved survival even without proven infection.

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