oxidative stress – Page 4

Therapeutic Prospects of Undaria pinnatifida Polysaccharides: Extraction, Purification, and Functional Activity

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This review examines how to extract and purify beneficial compounds called polysaccharides from wakame seaweed (Undaria pinnatifida), a popular food in East Asia. These polysaccharides have multiple health benefits including fighting oxidative damage, boosting immune function, fighting cancer cells, and promoting healthy gut bacteria. The review details various extraction methods and discusses how these compounds could be developed into functional foods and medicines.

Exploring Bacterial Interactions Under the Stress Gradient Hypothesis in Response to Selenium Stress

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This research reviews how bacteria respond to selenium pollution. Under low selenium stress, bacteria compete with each other for resources. As selenium levels increase, bacteria begin helping each other survive by producing detoxifying compounds. Some bacteria can convert toxic selenium into harmless forms, protecting less-tolerant bacteria in their community. Understanding these interactions helps us develop better strategies for cleaning up selenium-contaminated environments.

Bioactive Potential of Balkan Fomes fomentarius Strains: Novel Insights into Comparative Mycochemical Composition and Antioxidant, Anti-Acetylcholinesterase, and Antiproliferative Activities

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This study examines three strains of Fomes fomentarius mushroom from the Balkan region, revealing they are rich sources of beneficial compounds including polyamines and phenolic compounds. These extracts demonstrated strong antioxidant properties and potential neuroprotective effects, suggesting they could help prevent diseases related to oxidative stress and aging. The research supports the traditional use of this mushroom in folk medicine and highlights its potential as a natural supplement for health promotion.

Unveiling the Therapeutic Potentials of Mushroom Bioactive Compounds in Alzheimer’s Disease

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Mushrooms contain special compounds that may help protect the brain from Alzheimer’s disease. Research shows that eating mushrooms regularly could reduce the risk of memory problems and cognitive decline in older adults. These compounds work by reducing brain inflammation, protecting nerve cells, and helping the brain clear out harmful proteins. While these findings are promising, more human studies are needed to confirm how effective mushrooms are as an Alzheimer’s treatment.

Antioxidative Activities of Micronized Solid-State Cultivated Hericium erinaceus Rich in Erinacine A against MPTP-Induced Damages

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Researchers tested a processed form of Lion’s mane mushroom (Hericium erinaceus) to see if it could protect against Parkinson’s disease-like damage in mice. The mushroom mycelium was specially processed to break down cell walls and increase its effectiveness. When given to mice exposed to a Parkinson’s-causing toxin, the mushroom treatment restored dopamine levels and reduced harmful oxidative stress in the brain and liver in a dose-dependent manner.

Traditional Chinese Medicine for Hashimoto’s Thyroiditis: Focus on Selenium and Antioxidant Phytochemicals

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Hashimoto’s thyroiditis is a common autoimmune thyroid disease that often leads to symptoms like fatigue and reduced quality of life. While standard treatment uses thyroid hormone replacement, it doesn’t address the underlying inflammation and oxidative stress. This review explores how traditional Chinese medicine approaches, often combined with selenium, may help reduce thyroid antibodies and improve symptoms through their antioxidant and anti-inflammatory properties.

Neuroprotective Effects of Mushroom Biomass Digestive Fractions and Gut Microbiota Metabolites in Microglial and Caenorhabditis elegans Models of Neurodegeneration

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This study tested whether common and medicinal mushrooms could protect against Alzheimer’s disease by reducing harmful reactive oxygen species in brain cells. Researchers tested three mushroom types using digestive simulation to see what the body could absorb, plus key compounds made by gut bacteria. The mushroom extracts and certain bacterial metabolites successfully reduced cellular damage markers and improved behavior in disease-model worms, suggesting mushroom-rich diets may help prevent neurodegeneration.

The protecting role of Ganoderma lucidum polysaccharides on the retinal neurovascular units in rats with retinal ischemia-reperfusion injury

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This research demonstrates that polysaccharides extracted from Ganoderma lucidum mushrooms can protect rat retinas from damage caused by blocked and then restored blood flow. The treatment reduced cell death, decreased harmful oxidative stress, reduced inflammation-like responses from support cells, and improved retinal electrical function. These findings suggest that Ganoderma lucidum could potentially be developed as a therapeutic option for eye diseases like glaucoma and diabetic retinopathy where blood flow to the retina is compromised.

Ergothioneine: An Antioxidative, Neuroprotective and Anti-Inflammatory Compound from Mushroom Residuals

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Ergothioneine is a powerful antioxidant found mainly in mushrooms that protects brain health and reduces inflammation. Mushroom processing creates large amounts of waste like stems and leftover substrate that actually contain high levels of this beneficial compound. Scientists have developed sustainable methods to extract ergothioneine from this waste, creating opportunities for new health supplements and functional foods while reducing waste and supporting environmental sustainability.

Context-Dependent Fitness Trade-Offs in Penicillium expansum Isolates Resistant to Multiple Postharvest Fungicides

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This research examines how apples and pears get a fungal disease called blue mold and how the fungus develops resistance to commonly used fungicides. Scientists tested fungus samples that resist different fungicides to see if this resistance makes them weaker. They found that resistant fungus strains do struggle more under stressful laboratory conditions, but remain dangerous during long-term cold storage of fruit, especially when fungicides are present.

Research Keyword: oxidative stress