Research Keyword: oxidative stress

The Major Stilbene Compound Accumulated in the Roots of a Resistant Variety of Phoenix dactylifera L. Activates Proteasome for a Path in Anti-Aging Strategy

Researchers found that date palm roots from disease-resistant varieties contain a special compound called 3,3′,4,5,5′-pentahydroxy-trans-stilbene that acts as a natural antioxidant and anti-aging agent. This compound can protect aging skin cells by activating the proteasome, which is like the cell’s recycling system that removes damaged proteins. The findings suggest this natural compound could potentially help slow down skin aging and protect against age-related diseases.

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Hypoglycemic Effect of Pleurotus citrinopileatus and Hericium erinaceus Buccal Tablets on Diabetic Mice

Researchers created special tablets from two edible mushrooms (yellow oyster mushroom and lion’s mane) enriched with trace elements (chromium, zinc, germanium) to treat diabetes in mice. After three weeks of treatment, the high-dose tablets reduced blood sugar levels by 29%, improved cholesterol levels, boosted the body’s natural antioxidant defenses, and shifted the gut bacteria toward beneficial types that support metabolic health. These results suggest that mushroom-based treatments could potentially offer a natural way to help manage diabetes.

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Natural Neuroinflammatory Modulators: Therapeutic Potential of Fungi-Derived Compounds in Selected Neurodegenerative Diseases

This comprehensive review explores how compounds found in mushrooms could help treat serious brain diseases like Alzheimer’s and Parkinson’s disease. Mushrooms contain natural substances such as certain carbohydrates, proteins, and fats that can reduce harmful inflammation in the brain and protect nerve cells from damage. Scientists have tested these mushroom-derived compounds in laboratory and animal models, finding they can improve memory, movement, and overall brain function. This research suggests mushrooms could become an important part of new treatments for these currently incurable neurological conditions.

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Corrigendum: Compounds purified from edible fungi fight against chronic inflammation through oxidative stress regulation

This article is a correction to a previous study about beneficial compounds found in edible mushrooms. The study examined how various mushroom-derived substances like polysaccharides and peptides can combat chronic inflammation by reducing oxidative stress in the body. Multiple mushroom species were analyzed for their antioxidant properties and mechanisms of action. The corrections ensure proper citation of the original research sources while maintaining the core scientific findings.

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Enhanced Heat Resistance in Morchella eximia by Atmospheric and Room Temperature Plasma

Researchers used a special plasma technology to create heat-resistant strains of morel mushrooms that can thrive at higher temperatures. These mutant strains showed enhanced natural defense systems with more antioxidant enzymes and protective compounds. This breakthrough could help farmers grow more morels successfully despite rising temperatures from climate change, while maintaining their nutritional and medicinal benefits.

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Natural Products in Renal-Associated Drug Discovery

This research examines how natural products like green tea and medicinal mushrooms can help treat kidney diseases. Scientists reviewed various plants used in traditional medicine and analyzed how compounds from these plants affect gene expression in kidney cells. The study identified specific genes and biological pathways that explain how these natural antioxidants and anti-inflammatory agents protect kidneys from injury and disease.

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Tolerance and antioxidant response to heavy metals are differentially activated in Trichoderma asperellum and Trichoderma longibrachiatum

This research examined how two types of fungi called Trichoderma respond to contamination from heavy metals like copper, lead, and chromium. The study found that one species (T. longibrachiatum) is better at surviving heavy metal exposure than the other. Both species activate defensive mechanisms to combat the toxic effects, including producing protective proteins and enzymes that neutralize harmful molecules called reactive oxygen species.

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Growth Phase-Dependent Changes in the Carbohydrate Metabolism of Penicillium Strains from Diverse Temperature Classes in Response to Cold Stress

This study examined how three types of fungus respond to cold temperatures by measuring changes in their metabolic enzymes. Researchers exposed young and old fungal cells to cold stress and found that cold temperatures increased enzyme activity in both energy production pathways. Interestingly, the Antarctic psychrotolerant fungus adapted better to cold than the mesophilic fungi, showing that cold-adapted organisms have superior strategies for surviving freezing conditions.

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Strategies for Enhancing Resilience in Horticultural Crops Against Combined Abiotic Stresses

As climate change brings more extreme weather, vegetable and fruit crops face multiple environmental challenges simultaneously, like drought, high salt content, and heat. Scientists have developed practical approaches to make these crops stronger, including breeding tougher varieties, grafting plants onto hardy rootstocks, and applying special nanoparticles and natural plant boosters. These combined strategies help crops survive harsh conditions while maintaining good yields and quality, supporting food security for growing populations worldwide.

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2-Nonanol produced by Bacillus velezensis EM-1: a new biocontrol agent against tobacco brown spot

Researchers discovered that a beneficial bacterium called Bacillus velezensis produces a natural compound called 2-nonanol that effectively kills the fungus causing brown spots on tobacco leaves. This compound works by disrupting the fungus’s ability to obtain energy and handle stress. Testing on tobacco leaves showed that 2-nonanol could significantly reduce disease development. This discovery offers a promising environmentally-friendly alternative to chemical fungicides for protecting tobacco crops.

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