oxidative stress – Page 10

A Zn2-Cys6 transcription factor, TgZct4, reprograms antioxidant activity in the fungus Trichoderma guizhouense to defend against oxidative stress

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Trichoderma guizhouense is a fungus used to protect plants from harmful pathogens. Researchers discovered that a special protein called TgZct4 acts like a master switch that activates the fungus’s defense system against harmful reactive oxygen molecules. When the fungus encounters stress, TgZct4 turns on genes that produce protective enzymes called catalases and superoxide dismutases, helping the fungus survive. This discovery could help scientists create even more effective biological pest control products.

A Possible Involvement of Sialidase in the Cell Response of the Antarctic Fungus Penicillium griseofulvum P29 to Oxidative Stress

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Researchers studied a special fungus from Antarctica that produces an enzyme called sialidase. When temperatures dropped dramatically, the fungus activated this enzyme along with other protective defenses to survive. The study found that under extreme cold stress, sialidase activity increased significantly, suggesting it helps the fungus protect itself from oxidative damage caused by freezing temperatures. This is the first discovery showing sialidase plays an important role in how Antarctic fungi survive in their extreme environment.

Fungal-fungal cocultivation alters secondary metabolites of marine fungi mediated by reactive oxygen species (ROS)

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Researchers discovered that when two types of ocean fungi grow together, one of them produces a protective chemical called alternariol that can kill bacteria and cancer cells. This happens because the fungi recognize each other as competitors and trigger special stress signals that activate defensive chemical production. Interestingly, fungi from the ocean respond differently than those from land, suggesting they have evolved unique survival strategies for harsh marine environments.

Modulation of Abortiporus biennis Response to Oxidative Stress by Light as a New Eco-Friendly Approach with a Biotechnological Perspective

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Researchers studied how a type of fungus called Abortiporus biennis responds to stress created by a chemical compound (menadione) and different colors of light. They found that combining white light with menadione dramatically increased the production of laccase, an important enzyme used in industrial applications. This discovery offers an inexpensive, non-toxic way to boost enzyme production without using expensive chemical additives, potentially improving medical and industrial uses of this fungus.

Carabrone inhibits Gaeumannomyces tritici growth by targeting mitochondrial complex I and destabilizing NAD⁺/NADH homeostasis

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Researchers identified how carabrone, a natural compound from plants, kills a fungus that causes wheat disease. The compound works by blocking a key energy-producing system (complex I) inside the fungus’s cells, which prevents it from producing enough energy to survive. This discovery is important because many current fungicides are losing effectiveness due to resistance, and this compound offers a new way to attack fungi. The findings could help develop new and more effective fungicides for protecting crops.

Inhibitory Effect and Mechanism of Dryocrassin ABBA Against Fusarium oxysporum

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Researchers found that dryocrassin ABBA, a compound from a traditional East Asian fern, can effectively kill the fungus that causes potato rot disease. The compound damages the fungus by increasing harmful reactive oxygen species and disrupting the fungus’s ability to break down plant cell walls. This natural substance could potentially replace synthetic chemical fungicides, offering a safer and more environmentally friendly way to protect potatoes from disease.

Asymmetric mitonuclear interactions trigger transgressive inheritance and mitochondria-dependent heterosis in hybrids of the model system Pleurotus ostreatus

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This research examines how mushroom hybrids inherit different combinations of genes from their parents, specifically looking at genes in the nucleus versus the mitochondria (cellular energy factories). When mushrooms with mismatched nuclear and mitochondrial genes are crossed, some grow slowly and show stress, while others surprisingly grow very well. The study identifies which genes are activated under these conditions and how they affect mushroom production quality and yield.

Antimicrobial effects and mechanisms of hydrogen sulphide against nail pathogens

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Researchers discovered that hydrogen sulphide (H2S), a small gas molecule, can effectively kill the fungi and bacteria that cause painful nail infections. Unlike current treatments that struggle to penetrate into the nail, hydrogen sulphide easily diffuses through the nail plate. The study found that H2S works by damaging the fungi’s respiratory system and creating harmful reactive oxygen species, while also modifying proteins in a way that disrupts their normal function. This innovative approach could offer patients a new topical treatment option for nail infections that have been difficult to treat with existing medications.

Impact of a Formulation Containing Chaga Extract, Coenzyme Q10, and Alpha-Lipoic Acid on Mitochondrial Dysfunction and Oxidative Stress: NMR Metabolomic Insights into Cellular Energy

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A new supplement formula combining Chaga mushroom extract, Coenzyme Q10, and alpha-lipoic acid was tested on nerve cells in the laboratory. The formula increased the cells’ energy production and protected them from harmful oxidative stress. This could potentially help people with conditions like fibromyalgia and neurodegenerative diseases that involve mitochondrial dysfunction.

A Possible Involvement of Sialidase in the Cell Response of the Antarctic Fungus Penicillium griseofulvum P29 to Oxidative Stress

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Scientists studied a fungus from Antarctica to understand how it survives in extremely cold conditions. They discovered that when exposed to cold temperatures, this fungus produces more of an enzyme called sialidase, which appears to help protect cells from damage caused by reactive oxygen molecules. This finding adds to our understanding of how microorganisms adapt and survive in the world’s harshest environments.

Research Keyword: oxidative stress