oral candidiasis – mycolab.ai

Antifungal Efficacy of Ganoderma lucidum and Clotrimazole for Treatment of Denture Stomatitis: A Randomized Clinical Trial

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This study tested whether Ganoderma lucidum, a medicinal mushroom used in traditional Asian medicine, could treat denture stomatitis as effectively as the standard treatment clotrimazole. Both treatments reduced pain and improved symptoms equally well over two weeks. The results suggest that Ganoderma lucidum could be a useful alternative for patients who don’t respond well to standard antifungal drugs.

Antifungal Effects of Pterostilbene on Candida albicans, Candida dubliniensis, and Microcosm Biofilms of Denture Stomatitis

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Pterostilbene, a natural compound found in blueberries and grapes, has been shown to effectively kill Candida fungi that cause denture-related mouth infections. In laboratory tests, it successfully eliminated fungal cells and disrupted harmful biofilms within 8 hours. When tested in a living organism model, pterostilbene proved safe and reduced infection severity, suggesting it could be a promising natural alternative to conventional antifungal medications.

Evaluation of Antifungal Activity Against Candida albicans Isolates From HIV-Positive Patients with Oral Candidiasis in a Major Referral Hospital, West Java, Indonesia

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This study examined fungal infections in HIV-positive patients suffering from oral candidiasis (mouth thrush) in Indonesia. Researchers identified the types of Candida fungi present and tested their resistance to four common antifungal medications. Most patients had Candida albicans, and while these fungi generally responded well to newer antifungal drugs like voriconazole and fluconazole, some showed resistance, particularly to fluconazole, suggesting the need for careful testing before prescribing treatment.

Evaluation of antifungal effect of amphotericin B in comparison with nystatin on Candida species derived from patients undergoing head-and-neck radiotherapy

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This study compared two antifungal medications (nystatin and amphotericin B) for treating oral yeast infections in cancer patients receiving head-and-neck radiotherapy. Researchers tested how well each drug worked against different Candida yeast species before and during radiation treatment. The results showed that nystatin was more effective than amphotericin B at killing the yeasts, with nystatin working against all yeast species tested, while amphotericin B had reduced effectiveness against some Candida albicans strains.

Antifungal Potential of Streptomyces-Derived Metabolites Against Fluconazole-Resistant Oral Candida albicans: In vitro Evaluation and Mechanistic Insights

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Researchers studied a type of soil bacteria called Streptomyces that produces natural compounds with strong antifungal properties. These compounds effectively killed drug-resistant Candida fungal infections that commonly affect cancer patients undergoing radiation therapy. The bacterial extract worked by damaging fungal cell membranes and blocking biofilm formation, which are protective structures the fungus uses to survive. While the results are promising for treating stubborn fungal infections, more research is needed to ensure safety for human patients.

Evaluation of Antifungal Activity Against Candida albicans Isolates From HIV-Positive Patients with Oral Candidiasis in a Major Referral Hospital, West Java, Indonesia

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This study examined fungal infections of the mouth in HIV-positive patients in Indonesia. Researchers identified different types of Candida fungi and tested how well common antifungal medications worked against them. While most medications were effective, they found some cases of drug resistance, suggesting the importance of proper testing to choose the best treatment for each patient.

Antifungal efficacy of caffeic acid and nano-caffeic acid particles against candidiasis: an in vitro study

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Researchers developed a nano-particle form of caffeic acid, a natural compound found in coffee and tea, to treat oral yeast infections (candidiasis). The nano-version showed better antifungal activity than regular caffeic acid, though not as strong as prescription antifungal drugs. Since it comes from plants with fewer side effects, it could offer an alternative treatment option for patients with candidiasis.

Evaluation of Antifungal Activity Against Candida albicans Isolates From HIV-Positive Patients with Oral Candidiasis in a Major Referral Hospital, West Java, Indonesia

mycolabadmin

Researchers in West Java, Indonesia studied fungal infections in the mouths of HIV-positive patients to understand which antifungals work best. They found that a common fungal species called Candida albicans was present in all patients tested, though some resistant strains were discovered. The study showed that certain antifungal medications like voriconazole worked better than others, highlighting the importance of testing which specific medications will be effective for each patient rather than guessing.

Research Keyword: oral candidiasis