Research Keyword: One Health framework

Heavy Metal-Contaminated Soils and Gastric Cancer Risk: Molecular Insights and the Relevance of a One Health Perspective

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Heavy metals like cadmium, arsenic, and lead contaminate agricultural soils and accumulate in crops such as rice and vegetables, which people consume as part of their daily diet. These metals damage stomach cell DNA and trigger inflammation, increasing cancer risk, especially when combined with bacterial infections like H. pylori. A comprehensive approach monitoring soil quality, crop safety, and human health together can help prevent this disease and protect communities from contamination.

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Wildlife Dermatophytoses in Central Italy (Umbria and Marche Regions): A Fifteen-Year Investigation (2010–2024)

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Researchers studied fungal skin infections in wild animals across two Italian regions over 15 years, finding that about 11% carried dermatophyte fungi. Grey squirrels were most commonly infected, and some of these fungi can spread to humans through contact. The study highlights how wild animals act as sentinels for emerging diseases and emphasizes the importance of protective equipment when handling wildlife.

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Climate Change, Natural Disasters, and Cutaneous Fungal Infections

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Climate change and natural disasters are creating conditions that allow fungal infections to spread more easily and affect people in new ways. Warmer temperatures help fungi adapt to infect humans, while floods, earthquakes, and hurricanes expose people to fungal spores and create wounds through which infections can enter. Doctors need to be alert for unusual fungal infections after disasters, especially since some of these infections can cause serious complications and resist common treatments.

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Changing Climate, Changing Candida: Environmental and Social Pressures on Invasive Candidiasis and Antifungal Resistance in Latin America

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Invasive fungal infections caused by Candida yeasts are becoming more serious in Latin America, with drug-resistant strains spreading rapidly in hospitals. The problem is worsened by climate change and overuse of antifungal medicines in agriculture, which help resistant fungi survive and spread. Many hospitals in the region lack modern diagnostic tools to quickly identify the specific type of infection, delaying treatment. The authors recommend a comprehensive approach combining better environmental monitoring, smarter use of antifungal drugs, improved diagnostic access, and coordinated public health efforts across the region.

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Prevalence of fungi and their antifungal and disinfectant resistance in hospital environments: insights into combating nosocomial mycoses

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This study examined how fungal infections spread in hospital settings by testing air and surfaces in Iranian hospital intensive care units. Researchers found that dangerous fungi like Aspergillus and Rhizopus were commonly present, especially in air ducts, and many of these fungi could resist common antifungal medications and disinfectants. The findings suggest that hospital environments serve as sources of infection for vulnerable patients and that better cleaning and air filtration systems are needed to protect hospitalized patients.

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Changing Climate, Changing Candida: Environmental and Social Pressures on Invasive Candidiasis and Antifungal Resistance in Latin America

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Invasive fungal infections caused by Candida species are becoming increasingly common and dangerous in Latin American hospitals, with newer strains showing resistance to multiple antifungal drugs. Rising temperatures from climate change and widespread use of fungicides in agriculture appear to be selecting for these resistant fungi. Most hospitals in the region lack advanced diagnostic tools to quickly identify which fungal strain is causing infection, leading to delayed and sometimes inappropriate treatment. Implementing better diagnostic access, stricter antifungal use policies, and coordinated surveillance programs across the region could help control this growing public health problem.

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