Research Keyword: observational studies

Risk factors for invasive fungal infections in adult patients with hematological malignancies and/or stem cell transplant: a systematic review and meta-analysis

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This comprehensive study analyzed multiple research papers to identify which patients with blood cancers or stem cell transplants are most likely to develop serious fungal infections. The researchers found that patients who previously had a stem cell transplant, those taking corticosteroids, and those with low white blood cell counts face the highest risks. Importantly, the study showed that using antifungal medications as a preventive treatment significantly reduces infection risk in these vulnerable patients.

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Prevalence of Compartment Syndrome and Disseminated Intravascular Coagulation following Rhabdomyolysis; a Systematic Review and Meta-Analysis

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This study analyzed twenty research papers to understand how often two serious complications occur in patients with rhabdomyolysis, a condition involving muscle damage. Compartment syndrome, where pressure builds up around muscles limiting blood flow, occurred in about 4% of cases overall but was slightly more common in severe cases. Disseminated intravascular coagulation, a dangerous blood clotting disorder, occurred in about 8% of patients. These findings help doctors better understand and monitor for these potentially life-threatening complications.

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