Research Keyword: nutritional intervention

Nutritional strategies in supporting immune checkpoint inhibitor, PI3K inhibitor, and tyrosine kinase inhibitor cancer therapies

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This review examines how nutrition and food-based interventions can improve cancer treatment outcomes for patients receiving targeted cancer therapies. A Mediterranean-style diet with plenty of fiber (30-50g daily) appears beneficial for patients on immune checkpoint inhibitor therapies by promoting healthy gut bacteria that support immune function. The review also discusses promising research on fermented foods, specific bacterial supplements, mushroom extracts, and fasting approaches as complementary strategies to enhance cancer treatment effectiveness while reducing side effects.

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Mycelium: A Nutrient-Dense Food To Help Address World Hunger, Promote Health, and Support a Regenerative Food System

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Mycelium, the thread-like root structure of fungi, could help solve world hunger by providing nutritious, sustainable protein in just days. Unlike meat production which takes months to years, mycelium grows rapidly using minimal water and produces far less greenhouse gas. Early research suggests it may help lower cholesterol and improve blood sugar control while supporting a healthier planet.

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Antrodia Camphorata Supplement in the Early Life Inhibits Intestinal Tumorigenesis Later in Young Adult APC1638N Mice

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Researchers found that a mushroom supplement called Antrodia camphorate, when given to mice during childhood and adolescence, helped prevent intestinal tumors when the mice reached young adulthood. This effect was especially strong in mice that ate a high-fat diet early in life. The supplement appears to work by reducing inflammation and blocking certain proteins involved in tumor growth.

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Diet-Derived Advanced Glycation End-Products (AGEs) Induce Muscle Wasting In Vitro, and a Standardized Vaccinium macrocarpon Extract Restrains AGE Formation and AGE-Dependent C2C12 Myotube Atrophy

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This research shows that processed foods high in sugar and fat create harmful compounds called AGEs that can cause muscle loss and weakness. Cranberry extract, which contains natural antioxidants, was found to be particularly effective at blocking AGE formation and preventing muscle cell damage. The study suggests that eating foods containing cranberry extract might help prevent age-related muscle loss and the negative effects of unhealthy Western diets on muscle health.

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Long-Term Food Variety and Dietary Patterns Are Associated with Frailty among Chinese Older Adults: A Cohort Study Based on CLHLS from 2014 to 2018

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This study found that older Chinese adults who maintained a varied diet over four years had significantly lower rates of frailty compared to those with limited food variety. Two specific eating patterns were particularly beneficial: one including eggs, beans, pickles and some sugar, and another rich in fruits, vegetables, meat and fish. The findings suggest that encouraging elderly people to eat a diverse range of foods consistently over time may help prevent frailty and maintain better health in later life.

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