Research Keyword: nosocomial outbreak

Development of reverse transcription loop-mediated isothermal amplification-based assay for rapid and specific detection of human fungal pathogen, Candida auris

Researchers developed a new rapid test called RT-LAMP to detect Candida auris, a dangerous multidrug-resistant fungus that causes hospital infections. The test works by changing color from pink to yellow when the fungus is present, making it easy to read without special equipment. It is more sensitive and specific than current methods, can be done quickly at a single temperature, and costs much less than existing tests, making it ideal for hospitals and clinics with limited resources.

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Detection of Multiple Nosocomial Trichosporon asahii Transmission Events via Microsatellite Typing Assay, South America

Researchers developed a new genetic fingerprinting test to track and identify outbreaks of a dangerous fungal infection called Trichosporon asahii in hospitals across South America. The test uses microsatellite markers to create a detailed genetic profile of different fungal isolates, making it much better at detecting when infections spread from patient to patient compared to older methods. This discovery revealed multiple hidden disease clusters in hospitals, including one that occurred over 13 years, highlighting the importance of this new surveillance tool for hospital infection control.

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Photo Quiz: Unexpected yeast in a premature infant—pathogen or passenger

A newborn baby born very prematurely developed a yeast organism called Malassezia pachydermatis in a sputum sample, which was identified in the hospital laboratory. Researchers investigated whether this yeast was causing a serious infection or was just a harmless colonizer. Follow-up testing showed no infection, and the baby improved without antifungal treatment, suggesting it was contamination rather than true disease. However, this finding is important because this yeast has been known to cause serious infections in premature babies in hospital settings.

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