Research Keyword: nosocomial infections

Molecular Identification of Candida Species among Iranian Patients: Pursuing Candida auris

mycolabadmin

Researchers in Iran studied 136 hospital patients to identify different types of Candida fungal infections using a molecular laboratory technique called PCR-RFLP. They found that while Candida albicans remained the most common species, other Candida species were increasingly prevalent in hospitalized patients. The study developed a cost-effective diagnostic method that could help developing countries identify these fungal infections faster and more accurately, though the dangerous multidrug-resistant Candida auris was not found in their samples.

Read More »

Do farnesol and tyrosol production in Candidozyma auris biofilms reflect virulence potential?

mycolabadmin

Researchers discovered that a dangerous fungus called Candidozyma auris produces signaling molecules called farnesol and tyrosol in biofilms. These molecules appear to be linked to how dangerous the fungus is—strains that produce more of these molecules were more virulent in infection studies. Understanding these signaling molecules could help develop new strategies to fight this drug-resistant pathogen.

Read More »

Characterization of ORF19.7608 (PPP1), a biofilm-induced gene of Candida albicans

mycolabadmin

Researchers studied a gene called PPP1 in Candida albicans, a common fungal infection in hospitals. They found that this gene is highly active when the fungus forms protective biofilms on medical devices like catheters. Although the protein appears in a distinctive spotted pattern only during biofilm formation, removing this gene did not prevent biofilm formation or affect how the fungus responds to stress or antifungal drugs.

Read More »

Brown locusts, Locustana pardalina, host fluconazole-resistant Candidozyma (Candida) auris, closely related to Clade III clinical strains

mycolabadmin

Researchers discovered that brown locusts in South Africa can carry a dangerous drug-resistant fungus called Candida auris in their digestive systems. This fungus, which causes serious infections in hospitals and is resistant to the antifungal drug fluconazole, may use locusts as a way to spread to humans or other environments. The study suggests that insects could play an important role in how dangerous fungi emerge and spread globally, particularly in warm climates where locusts thrive.

Read More »

Invasive Candidiasis in Contexts of Armed Conflict, High Violence, and Forced Displacement in Latin America and the Caribbean (2005–2025)

mycolabadmin

This comprehensive review examines candida fungal infections in conflict-affected areas of Latin America and the Caribbean, where wars, violence, and displacement create dangerous conditions that make infections more likely and harder to treat. In these regions, mortality from candida bloodstream infections reaches 65% or higher among displaced populations, compared to about 45-60% in regular hospitals. The main problems are lack of proper diagnostic equipment, limited access to effective antifungal medications, malnutrition, overcrowding in shelters, and the emergence of drug-resistant fungal strains.

Read More »
Scroll to Top