Research Keyword: NMR spectroscopy

Isolation, Characterization, and Wound-Healing Potential of β-D-Glucan from Lycoperdon pyriforme Schaeff

Researchers isolated and studied a compound called β-D-glucan from puffball mushrooms (Lycoperdon pyriforme) that have been traditionally used to heal wounds and stop bleeding. Laboratory tests showed this compound safely promotes the movement and growth of skin cells that help wounds close without harming red blood cells, and it actually helps blood clot faster. These findings support the traditional use of this mushroom and suggest it could be developed into a new natural wound-healing treatment.

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Anti-Xanthine Oxidase 5′-Hydroxyhericenes A–D from the Edible Mushroom Hericium erinaceus and Structure Revision of 3-[2,3-Dihydroxy-4-(hydroxymethyl)tetrahydrofuran-1-yl]-pyridine-4,5-diol

Researchers isolated new compounds from Lion’s mane mushroom (Hericium erinaceus) that can inhibit xanthine oxidase, an enzyme linked to breast cancer development. One compound called hericerin showed strong activity against a specific type of breast cancer cell (T47D cells) while being less harmful to normal cells. The study also corrected a misidentification from previous research, confirming that a compound previously thought to have a different structure was actually adenosine. These findings suggest Lion’s mane could be developed into a natural anti-cancer treatment.

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First Chemical Investigation of Korean Wild Mushroom, Amanita hemibapha subsp. javanica and the Identification of Anti-Helicobacter pylori Compounds

Researchers studied a Korean edible mushroom called Amanita hemibapha subsp. javanica and found it contains compounds that can kill the bacteria Helicobacter pylori, which causes stomach ulcers and gastric cancer. One compound in particular showed strong antibacterial activity, performing even better than some known antibiotics. These findings suggest this mushroom could be a natural source for developing new medicines to treat H. pylori infections and fight antibiotic-resistant strains.

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Isolation and Identification of Chemical Compounds from Agaricus blazei Murrill and Their In Vitro Antifungal Activities

Researchers extracted and identified six chemical compounds from A. blazei mushrooms and tested their ability to fight fungal infections. The compounds showed promising activity against common fungal pathogens that cause infections in humans. This research suggests that A. blazei could be developed into natural antifungal treatments. The findings add to growing evidence that medicinal mushrooms contain valuable bioactive compounds with therapeutic potential.

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The Major Stilbene Compound Accumulated in the Roots of a Resistant Variety of Phoenix dactylifera L. Activates Proteasome for a Path in Anti-Aging Strategy

Researchers found that date palm roots from disease-resistant varieties contain a special compound called 3,3′,4,5,5′-pentahydroxy-trans-stilbene that acts as a natural antioxidant and anti-aging agent. This compound can protect aging skin cells by activating the proteasome, which is like the cell’s recycling system that removes damaged proteins. The findings suggest this natural compound could potentially help slow down skin aging and protect against age-related diseases.

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Ergostane-type steroids from mushrooms of Pleurotus genus

Oyster mushrooms and king trumpet mushrooms contain special compounds called ergostane-type steroids that have interesting chemical structures. These compounds can fight inflammation and may help with cancer. Scientists have discovered that some of these compounds have unique rearranged structures that don’t exist in other organisms. These mushroom-derived compounds show promise for developing new medicines.

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Nicotine Degradation by Trametes versicolor: Insights from Diverse Environmental Stressors and Wastewater Medium

This study shows that a common mushroom fungus called Trametes versicolor can effectively break down and remove nicotine from wastewater. The research found that the fungus works best at room temperature and slightly acidic conditions, particularly when grown in wastewater-like media. The findings suggest this fungal approach could become an environmentally friendly way to clean up nicotine pollution in water systems.

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