nitric oxide – mycolab.ai

Biphasic Fermentation of Trapa bispinosa Shells by Ganoderma sinense and Characterization of Its Polysaccharides and Alcoholic Extract and Analysis of Their Bioactivity

mycolabadmin

This study investigated fermenting water chestnut shells with a medicinal mushroom called Ganoderma sinense to create a more potent health product. Under optimal fermentation conditions, the resulting material showed significantly improved immune-boosting and antioxidant properties when tested in laboratory cells. The fermentation process changed the structure of polysaccharides and increased beneficial compounds, potentially transforming agricultural waste into a valuable functional food or supplement.

Activation of chicken macrophages by isomalto/malto-polysaccharide (IMMP) is facilitated by toll-like receptor 4 (TLR4)

mycolabadmin

Researchers studied how a natural carbohydrate called IMMP can boost chicken immune cells called macrophages. They found that IMMP activates these immune cells through a receptor called TLR4, making them more effective at fighting infections. This suggests IMMP could be added to poultry feed as a natural alternative to antibiotics to improve gut health and disease resistance in chickens.

Bioactive Potential of Tocosh Supplemented with Selenium-Enriched Saccharomyces Cerevisiae Biomass

mycolabadmin

Researchers enhanced a traditional Peruvian fermented potato food called tocosh by adding selenium-enriched yeast. This combination reduced inflammation markers in immune cells without affecting its blood sugar impact or antioxidant properties. The resulting product shows promise as a functional food that could help people manage inflammatory conditions while improving nutritional content.

Exogenous L-Arginine Enhances Pathogenicity of Alternaria alternata on Kiwifruit by Regulating Metabolisms of Nitric Oxide, Polyamines, Reactive Oxygen Species (ROS), and Cell Wall Modification

mycolabadmin

Researchers discovered that a specific nutrient called L-arginine paradoxically makes a fungus that causes black spot on kiwifruit more dangerous at low concentrations. The fungus uses this amino acid to trigger multiple survival mechanisms including producing protective molecules and enzymes that break down plant cell walls. However, at higher concentrations, L-arginine actually inhibits the fungus, suggesting it could be used as part of a disease control strategy.

Effects and molecular mechanism of endophytic elicitors on the accumulation of secondary metabolites in medicinal plants

mycolabadmin

This review explains how beneficial fungi living inside medicinal plants can boost the production of healing compounds. These endophytic fungi act as natural triggers that activate the plant’s own defense systems, causing it to produce more of the valuable medicinal substances used in traditional and modern medicine. By understanding how this process works, scientists can develop better methods to grow medicinal plants and produce natural drugs more sustainably without depleting wild plant populations.

Recent Discoveries on Marine Organism Immunomodulatory Activities

mycolabadmin

Scientists are discovering that creatures from the ocean produce powerful substances that can help our immune system fight diseases like cancer and inflammation. These marine organisms—from tiny algae to sponges to fish—create natural compounds that can either boost or calm down our immune response depending on what we need. Several of these ocean-derived medicines are already approved for treating serious diseases, and many more are being tested in clinical trials. The ocean covers 70% of our planet and most of it remains unexplored, suggesting there are many more beneficial compounds waiting to be discovered.

The Role of Nitric Oxide in the Growth and Development of Schizophyllum commune Under Anaerobic Conditions

mycolabadmin

This study shows that nitric oxide, a chemical messenger, plays an important role in helping a wood-decay fungus called Schizophyllum commune grow and reproduce in environments without oxygen. When nitric oxide levels are boosted, the fungus grows better and can even start forming fruiting bodies (mushrooms) under low-oxygen conditions. These findings could help scientists understand how fungi survive and thrive in extreme environments like deep ocean sediments.

Nitric Oxide-Mediated Regulation of Chitinase Activity and Cadmium Sequestration in the Response of Schizophyllum commune to Cadmium Stress

mycolabadmin

A culinary mushroom called Schizophyllum commune can be harmed by cadmium pollution. When exposed to cadmium, the fungus produces nitric oxide, which causes enzymes called chitinases to become more active. These active enzymes break down the mushroom’s cell wall, allowing more cadmium to accumulate and ultimately damage the fungus’s growth. By reducing nitric oxide levels, scientists may be able to protect this mushroom from cadmium poisoning.

Research Keyword: nitric oxide