Research Keyword: neutrophils

The Inhibitory Effects of Cordyceps militaris ARA301 Extract on Lipopolysaccharide-Induced Lung Injury in vivo

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Researchers tested a mushroom extract from Cordyceps militaris to see if it could protect mice from lung injury caused by bacterial toxins. The extract successfully reduced inflammation, prevented excessive mucus production, and decreased immune cell buildup in the lungs. These findings suggest that this mushroom extract could potentially be used as a natural supplement to help prevent respiratory diseases and support lung health.

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Fusarium Corneal Abscess: A Case Report

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A 20-year-old healthy patient developed a serious fungal eye infection caused by Fusarium, a common soil fungus, despite having no typical risk factors like eye trauma or contact lens wear. The infection created an abscess (collection of pus) in the cornea and threatened the patient’s vision. Doctors used a combination of antifungal medications and eventually transplanted amniotic membrane tissue to prevent the cornea from rupturing, preserving the patient’s eyesight.

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The C-type lectin receptor Dcir (Clec4a2) restrains Aspergillus fumigatus elimination by limiting the degranulatory activity of neutrophils

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This study reveals that a receptor called Dcir on immune cells called neutrophils actually prevents effective killing of the fungus Aspergillus fumigatus by limiting the release of antibacterial granules. When researchers removed Dcir from mice, their neutrophils became more effective at fighting the fungal infection. This suggests that blocking Dcir might help patients with fungal respiratory infections clear the pathogen more effectively.

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