Research Keyword: Nephrolithiasis

A novel synbiotic formulation prevents calcium oxalate stones by restoring gut microbiota homeostasis

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This study tested a special probiotic and prebiotic combination to prevent kidney stones caused by too much oxalate in the body. The formula containing three beneficial bacteria strains and a plant-based fiber worked better than any single component alone. The treatment restored healthy gut bacteria, protected the intestinal lining, and reduced the amount of oxalate reaching the kidneys, effectively preventing stone formation in animal models.

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Urosepsis From Nephrolithiasis Caused by Candida glabrata: A Rare Etiology of Urinary Sepsis in an Immunocompetent Patient

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A 41-year-old man with kidney stones developed a serious bloodstream infection caused by Candida glabrata, a type of yeast fungus that rarely infects healthy people. Although he initially received antibiotics, his condition worsened until doctors identified the fungal infection through blood tests. After placing a drainage tube in his kidney and treating him with an antifungal medication called micafungin, he recovered well. This case highlights the importance of considering fungal infections when standard antibiotics fail to treat kidney stone-related infections.

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A cross-sectional study of the association between plant-based diet indices and kidney stones among Iranian adults

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A study of nearly 10,000 Iranian adults found that people who followed a plant-based diet had a higher risk of developing kidney stones. However, the quality of plant-based eating did not matter—neither healthful nor unhealthful plant-based diets changed the risk significantly. This suggests that while plant-based diets are generally healthy, people at risk for kidney stones should ensure adequate calcium intake and proper hydration.

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