Research Keyword: nematode-trapping fungi

Functions of the Three Common Fungal Extracellular Membrane (CFEM) Domain-Containing Genes of Arthrobotrys flagrans in the Process of Nematode Trapping

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Researchers studied how a fungus called Arthrobotrys flagrans catches and kills parasitic worms. They found that three genes containing a special protein domain called CFEM control how the fungus produces sticky traps and deadly proteins. By studying mutant fungi with these genes deleted or overexpressed, they discovered that these genes work together and can compensate for each other, helping explain how this fungus could be used as a natural pest control for harmful nematodes.

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The cysteine-rich virulence factor NipA of Arthrobotrys flagrans interferes with cuticle integrity of Caenorhabditis elegans

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Researchers discovered how a predatory fungus attacks roundworms by producing a special protein called NipA that weakens the worm’s protective outer layer. This cysteine-rich protein causes blister-like formations in the worm’s skin and disrupts the genes responsible for maintaining the protective barrier. Understanding this mechanism helps scientists learn how fungi infect organisms and could lead to better control methods for parasitic nematodes.

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Functions of the Three Common Fungal Extracellular Membrane (CFEM) Domain-Containing Genes of Arthrobotrys flagrans in the Process of Nematode Trapping

mycolabadmin

Researchers studied a special fungus called Arthrobotrys flagrans that traps and kills parasitic worms. They focused on three genes (AfCFEM1-3) that produce proteins important for making the sticky traps. When they removed two of these genes, the fungus became better at killing worms, while removing the third gene made it worse. The study shows these genes are crucial for the fungus to create effective sticky traps and could help develop better natural pest control products.

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