natural products chemistry

Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

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Researchers discovered a fungus living inside an Iranian medicinal plant that produces three natural compounds with powerful antimicrobial properties. The most promising compound, phomalactone, killed dangerous bacteria including MRSA and also prevented growth of fungal plant diseases. This discovery shows that exploring symbiotic fungi in medicinal plants could lead to new natural antibiotics and agricultural fungicides.

Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

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Researchers isolated eight new bioactive compounds from a rare European mushroom species called Hericium flagellum. These compounds showed promising ability to stimulate nerve cell growth and could potentially help treat neurodegenerative diseases like Alzheimer’s and Parkinson’s. The study demonstrates that mushroom-derived natural products may offer new therapeutic approaches for conditions affecting millions of elderly people worldwide.

Fungal inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta

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Researchers isolated six antifungal compounds from a traditional Chinese medicine plant called Laggera pterodonta. One compound called costic acid showed excellent ability to kill common crop-destroying fungi like P. nicotianae and F. oxysporum by damaging their cell membranes. These natural compounds could serve as safer alternatives to synthetic fungicides in agriculture, offering environmental benefits without toxic chemical residues.

Phytochemical Profile and Antimicrobial Activities of Edible Mushroom Termitomyces striatus

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Researchers studied an edible mushroom called Termitomyces striatus traditionally consumed in Africa and Asia to understand its disease-fighting properties. They found that extracts from this mushroom contain beneficial compounds that can kill harmful bacteria and fungi in laboratory tests. The dichloromethane extract was the most effective, showing strong activity against multiple disease-causing bacteria and the yeast Candida albicans. This suggests the mushroom could potentially be developed into new natural antimicrobial treatments.

Research Keyword: natural products chemistry

Extraction and Identification of the Bioactive Metabolites Produced by Curvularia inaequalis, an Endophytic Fungus Collected in Iran from Echium khuzistanicum Mozaff

Hericioic Acids A–G and Hericiofuranoic Acid; Neurotrophic Agents from Cultures of the European Mushroom Hericium flagellum

Fungal inhibitory activity of sesquiterpenoids isolated from Laggera pterodonta

Phytochemical Profile and Antimicrobial Activities of Edible Mushroom Termitomyces striatus