Research Keyword: natural antimicrobial agents

Antibiofilm activity and bioactive phenolic compounds of ethanol extract from the Hericium erinaceus basidiome

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Researchers tested a lion’s mane mushroom extract for its ability to stop harmful bacteria from forming protective biofilms that make infections harder to treat. The extract showed strong activity against Proteus mirabilis bacteria, reducing biofilm formation by over 78%. The antibiofilm power comes mainly from two phenolic compounds: protocatechuic acid and p-coumaric acid. These findings suggest lion’s mane mushroom could be developed into natural supplements or food preservatives to prevent bacterial contamination.

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Genome-Mining Based Discovery of Pyrrolomycin K and L from the Termite-Associated Micromonospora sp. RB23

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Scientists discovered two new antimicrobial compounds called pyrrolomycins from bacteria living in termites using genome sequencing and chemical analysis. These compounds contain chlorine atoms and are related to known antibiotics. The research shows how the bacteria protects itself from its own antimicrobial compounds through chemical modifications, offering insights into developing new antibiotics.

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Isolation and Identification of Aspergillus spp. from Rotted Walnuts and Inhibition Mechanism of Aspergillus flavus via Cinnamon Essential Oil

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Researchers collected rotted walnuts from storage in Shanxi, China and identified five types of Aspergillus fungi contaminating them, with Aspergillus flavus being the most common. They tested cinnamon essential oil as a natural antifungal treatment and found it effectively stopped fungal growth by damaging the fungi’s cell membranes and causing oxidative stress. This research suggests cinnamon essential oil could be used as a safe, natural alternative to chemical fungicides for preserving walnuts and other foods from fungal spoilage.

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