Research Keyword: natamycin

Two Cases of Curvularia geniculata Keratitis Successfully Treated with Natamycin-Based Therapy

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This report describes two patients who developed rare fungal eye infections caused by Curvularia geniculata after eye injuries. Both patients were successfully treated with antifungal eye drops, particularly natamycin. Molecular testing confirmed the specific fungus causing the infection. Both patients recovered well with excellent vision restoration, demonstrating that proper diagnosis and targeted antifungal treatment can effectively manage this rare condition.

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Two Cases of Curvularia geniculata Keratitis Successfully Treated with Natamycin-Based Therapy

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Two patients developed rare fungal eye infections caused by Curvularia geniculata after eye injuries from plant material. The infections caused corneal ulcers with characteristic feathery infiltrates. Both patients were successfully treated using natamycin eyedrops, either alone or combined with voriconazole, and both recovered excellent vision. Accurate identification of the fungus using genetic testing confirmed the diagnosis and helped guide treatment decisions.

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Favorable outcome of Lasiodiplodia theobromae keratomycosis: a clinical case and systematic review

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A 74-year-old farmer developed a serious fungal eye infection caused by Lasiodiplodia theobromae, a rare tropical fungus. Instead of requiring eye surgery, the patient was successfully treated with a combination of two antifungal medications applied as eye drops and taken orally for eight weeks. This case is significant because it’s the first documented successful medical treatment of this particular fungal infection, highlighting the importance of quick diagnosis and avoiding corticosteroid eye drops that can worsen fungal infections.

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First report of Stemphylium lycopersici keratitis, a complex corneal infection case

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A 66-year-old man developed a severe corneal infection from a stone chip injury that didn’t improve with standard antibiotics. Doctors discovered the infection was caused by a rare plant fungus called Stemphylium lycopersici, combined with a herpes virus. Using advanced genetic testing (mNGS) to identify the exact pathogens, they prescribed targeted antifungal and antiviral medications along with a corneal transplant, successfully healing the infection and preserving his vision.

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