Research Keyword: Nail fungal infection

Onychomycosis in the US Pediatric Population—An Emphasis on Fusarium Onychomycosis

This study examined nail fungus infections in American children using advanced molecular testing. Researchers found that elementary school-aged children (ages 6-11) have the highest rates of nail fungus, usually caused by common fungi like Trichophyton rubrum. Notably, Fusarium, an environmental fungus that was once rare in nail infections, is becoming increasingly common, especially in older teenagers, which may require different treatment approaches.

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Antimicrobial effects and mechanisms of hydrogen sulphide against nail pathogens

Researchers discovered that hydrogen sulphide (H2S), a small gas molecule, can effectively kill the fungi and bacteria that cause painful nail infections. Unlike current treatments that struggle to penetrate into the nail, hydrogen sulphide easily diffuses through the nail plate. The study found that H2S works by damaging the fungi’s respiratory system and creating harmful reactive oxygen species, while also modifying proteins in a way that disrupts their normal function. This innovative approach could offer patients a new topical treatment option for nail infections that have been difficult to treat with existing medications.

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